3.30 MB - Academy of Medicine of Malaysia

TABLE OF CONTENTS
MANAGEMENT OF HIV INFECTION IN CHILDREN
GUIDELINE DEVELOPMENT AND OBJECTIVE i
GUIDELINE DEVELOPMENT GROUP
REVIEW COMMITTEE vi
EXTERNAL REVIEWERS vii
ALGORITHM 1: MANAGMENT OF HIV EXPOSED INFANT viii
ALGORITHM 2: MEDICAL MANAGEMENT OF HIV ix
POSITIVE MOTHER vii
1 INTRODUCTION 1
2. MANAGEMENT OF THE PERINATALLY EXPOSED INFANT 2
2.1 HIV PROPHYLAXIS 2
2.2 EVALUATION & CARE AT BIRTH 6
2.3 INVESTIGATIONS AT BIRTH 7
2.4 ADVICE AND COUNSELLING 9
2.5 FEEDING 10
2.6 IMMUNISATION 11
2.7 CLINICAL AND LABORATORY MONITORING OF
THE PERINATALLY EXPOSED INFANT 16
2.8 PRIMARY PNEUMOCYSTIS JIROVECI PNEUMONIA
PROPHYLAXIS FOR THE TREATMENT PERINATTALLY
EXPOSED INFANT 18
3. MANAGEMENT OF HIV INFECTED INFANTS, 21
CHILDREN AND ADOLESCENT
3.1 MONITORING DISEASE PROGRESSION 21
3.2 ANTIRETROVIRAL THERAPY 21
3.2.1 Effectiveness of HAART
3.2.2 When to initiate therapy
3.2.3 Issues and choice for initial antiretroviral therapy
3.2.4 Special Issues For Adolescents
3.2.5 Treatment failure
3.2.6. Management of medication toxicity or intolerance
3.2.7 Short- term therapy interruption
4. COMMON OPPORTUNISTIC INFECTIONS (OI) AND
COMPLICATIONS IN HIV INFECTED CHILDREN 45
4.1 PATTERN OF OPPORTUNISTIC INFECTIONS 45
4.2 PREVENTING OPPORTUNISTIC INFECTIONS 45
4.2.1 Dosage and regimens for OI prophylaxis
4.2.2 Safety of PCP prophylaxis medications
11 x