3.30 MB - Academy of Medicine of Malaysia

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TABLE OF CONTENTS MANAGEMENT OF HIV INFECTION IN CHILDREN GUIDELINE DEVELOPMENT AND OBJECTIVE i GUIDELINE DEVELOPMENT GROUP REVIEW COMMITTEE vi EXTERNAL REVIEWERS vii ALGORITHM 1: MANAGMENT OF HIV EXPOSED INFANT viii ALGORITHM 2: MEDICAL MANAGEMENT OF HIV ix POSITIVE MOTHER vii 1 INTRODUCTION 1 2. MANAGEMENT OF THE PERINATALLY EXPOSED INFANT 2 2.1 HIV PROPHYLAXIS 2 2.2 EVALUATION & CARE AT BIRTH 6 2.3 INVESTIGATIONS AT BIRTH 7 2.4 ADVICE AND COUNSELLING 9 2.5 FEEDING 10 2.6 IMMUNISATION 11 2.7 CLINICAL AND LABORATORY MONITORING OF THE PERINATALLY EXPOSED INFANT 16 2.8 PRIMARY PNEUMOCYSTIS JIROVECI PNEUMONIA PROPHYLAXIS FOR THE TREATMENT PERINATTALLY EXPOSED INFANT 18 3. MANAGEMENT OF HIV INFECTED INFANTS, 21 CHILDREN AND ADOLESCENT 3.1 MONITORING DISEASE PROGRESSION 21 3.2 ANTIRETROVIRAL THERAPY 21 3.2.1 Effectiveness of HAART 3.2.2 When to initiate therapy 3.2.3 Issues and choice for initial antiretroviral therapy 3.2.4 Special Issues For Adolescents 3.2.5 Treatment failure 3.2.6. Management of medication toxicity or intolerance 3.2.7 Short- term therapy interruption 4. COMMON OPPORTUNISTIC INFECTIONS (OI) AND COMPLICATIONS IN HIV INFECTED CHILDREN 45 4.1 PATTERN OF OPPORTUNISTIC INFECTIONS 45 4.2 PREVENTING OPPORTUNISTIC INFECTIONS 45 4.2.1 Dosage and regimens for OI prophylaxis 4.2.2 Safety of PCP prophylaxis medications 11 x
MANAGEMENT OF HIV INFECTION IN CHILDREN 5. NON INFECTIOUS COMPLICATIONS OF HIV 47 5.1 MALIGNANCY 47 5.2 NEUROLOGIC COMPLICATIONS 47 5.3 HIV-ASSOCIATED NEPHROPAHY 48 5.4 CARDIAC COMPLICATIONS 48 5.5 LYMPHOCYTIC INTERSTITIAL PNEUMONITIS (LIP) 48 6. OTHER ISSUES 6.1 DISCLOSURE 48 6.2 AGE APPROPRIATE EDUCATIONAL & LIFESYLE ADVICE FOR CHILDREN AND ADOLESCENTS 51 REFERENCES 53-69 APPENDIX 1 - WHO clinical staging of HIV/AIDS for children with confirmed HIV infection 70 APPENDIX 2 - WHO clinical staging /AIDS for adults and adolescents with confirmed HIV infection 71 APPENDIX 3 - Immunological Classification 72 APPENDIX 4 - Antiretroviral Drugs 73-79 APPENDIX 5 - Tanner staging in adolescents 80 APPENDIX 6 - Investigations for opportunistic infections 82 APPENDIX 7 - Treatment for opportunistic infections 83-84 APPENDIX 8 - List of HIV Drugs Available in Malaysia 85 APPENDIX 9 - Additional Resources 86 LIST OF ABREVIATIONS 87 ACKNOWLEGEMENTS 88 DICLOSURE STATEMENT 88 SOURCES OF FUNDING 88 LEVEL OF EVIDENCE & GRADE OF RECOMMENDATION 12 xi
Page 2 and 3: This Guideline is intended a guide
Page 4 and 5: MANAGEMENT OF HIV INFECTION IN CHIL
Page 8 and 9: REVIEW COMMITTEE The draft guidelin
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MANAGEMENT OF HIV INFECTION IN CHIL
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71 Appendix 2 WHO CLINICAL STAGING
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Appendix 6 MANAGEMENT OF HIV INFECT
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Appendix 7 MANAGEMENT OF HIV INFECT
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3.30 MB - Academy of Medicine of Malaysia

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