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Fundamentals of epidemiology - an evolving text - Are you looking ...

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Margin <strong>of</strong> error (rounded)<br />

Point Sample Absolute * Relative **<br />

estimate size<br />

(%)<br />

0.1 100 0.06*** 60***<br />

0.2 100 0.08 40<br />

0.3 100 0.09 30<br />

0.4 100 0.096 24<br />

0.5 100 0.10 20<br />

0.6 100 0.096 16<br />

0.7 100 0.09 12<br />

0.8 100 0.08 9.8<br />

0.9 100 0.06 6.5<br />

0.1 400 0.03 30<br />

0.2 400 0.04 20<br />

0.3 400 0.045 15<br />

0.4 400 0.048 12<br />

0.5 400 0.05 10<br />

0.6 400 0.048 8.0<br />

0.7 400 0.045 6.4<br />

0.8 400 0.04 4.9<br />

0.9 400 0.03 3.2<br />

* Approximate half-width <strong>of</strong> 95% confidence interval in absolute terms<br />

** Approximate half-width <strong>of</strong> 95% confidence interval in absolute terms, relative to the size <strong>of</strong><br />

the point estimate<br />

*** Calculation: 1.96 (1/√[(0.01)(1 – 0.01) / 100]) = 1.96 (0.03) = 0.0588 ≈ 0.06 absolute<br />

error margin<br />

This table illustrates that:<br />

1. quadrupling sample size halves the margin <strong>of</strong> error.<br />

2. absolute error margin decreases as the point estimate moves away from 0.5<br />

3. relative error margin is inversely – <strong>an</strong>d very strongly – related to the size <strong>of</strong> the point<br />

estimate<br />

For very small point estimates, as illustrated in the following table, very large samples are required to<br />

obtain a small relative margin <strong>of</strong> error. Even a sample size <strong>of</strong> 2,500 still produces a relative error<br />

margin <strong>of</strong> 17% for a proportion <strong>of</strong> 0.05.<br />

_____________________________________________________________________________________________<br />

www.sph.unc.edu/courses/EPID 168, © Victor J. Schoenbach 14. Data <strong>an</strong>alysis <strong>an</strong>d interpretation – 490<br />

rev. 11/8/1998, 10/26/1999, 12/26/1999

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