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(12) International Application Status Report - Questel

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(<strong>12</strong>) <strong>International</strong> <strong>Application</strong> <strong>Status</strong> <strong>Report</strong><br />

Received at <strong>International</strong> Bureau: 31 December 2003 (31.<strong>12</strong>.2003)<br />

Information valid as of: Not available<br />

<strong>Report</strong> generated on: 24.07.2010<br />

(10) Publication number:<br />

WO2004/041118<br />

(21) <strong>Application</strong> Number:<br />

PCT/US2003/034643<br />

(43) Publication date:<br />

21 May 2004 (21.05.2004)<br />

(22) Filing Date:<br />

31 October 2003 (31.10.2003)<br />

(26) Publication language:<br />

English (EN)<br />

(25) Filing language:<br />

English (EN)<br />

(31) Priority number(s): (31) Priority date(s): (31) Priority status:<br />

60/423,260 (US) 31 October 2002 (31.10.2002) Priority document received (in compliance<br />

with PCT Rule 17.1)<br />

60/424,920 (US) 08 November 2002 (08.11.2002) Priority document received (in compliance<br />

with PCT Rule 17.1)<br />

60/425,655 (US) <strong>12</strong> November 2002 (<strong>12</strong>.11.2002) Priority document received (in compliance<br />

with PCT Rule 17.1)<br />

10/444,634 (US) 22 May 2003 (22.05.2003) Priority document received (in compliance<br />

with PCT Rule 17.1)<br />

(51) <strong>International</strong> Patent Classification:<br />

A61K 9/00 (2006.01); A61K 9/02 (2006.01); A61K 9/<strong>12</strong> (2006.01); A61K 9/70 (2006.01); A61K 31/192 (2006.01); A61K<br />

31/196 (2006.01); A61K 31/277 (2006.01); A61K 31/337 (2006.01); A61K 31/405 (2006.01); A61K 31/407 (2006.01); A61K<br />

31/5415 (2006.01); A61K 31/616 (2006.01); A61K 31/663 (2006.01); A61K 38/11 (2006.01); A61K 38/20 (2006.01); A61K 38/27<br />

(2006.01); A61K 38/28 (2006.01); A61K 45/06 (2006.01)<br />

(71) Applicant(s):<br />

UMD, INC. [US/US]; Suite 500 6954 Cornell Road Cincinnati, OH 45242 (US) (for all designated states)<br />

(72) Inventor(s):<br />

PAULETTI, Giovanni, M.; 11906 Streamside Drive Loveland, OH 95140 (US)<br />

DESAI, Kishorkumar, J.; 8648 Rupp Farm Drive Westchester, OH 45069 (US)<br />

ROWETON, Susan, L.; 2620-101 Garden Hill Drive Raleigh, NC 27614 (US)<br />

HARRISON, Donald, C.; 9250 Old Indian Hill Road Cincinnati, OH 45242 (US)<br />

SANDERS, Lynda, M.; 749 Anderson Drive Los Altos, CA 94024 (US)<br />

(74) Agent(s):<br />

VERNY, Hana; Peters, Verny, Jones & Schmitt LLP 425 Sherman Avenue, Suite 230 Palo Alto, CA 94306 (US)<br />

(54) Title (EN): THERAPEUTIC COMPOSITIONS FOR DRUG DELIVERY TO AND THROUGH COVERING EPITHELIA<br />

(54) Title (FR): COMPOSITIONS THERAPEUTIQUES POUR UNE ADMINISTRATION DE MEDICAMENT A<br />

L'EPITHELIUM DE SURFACE ET A TRAVERS L'EPITHELIUM COUVRANT<br />

(57) Abstract:<br />

(EN): Polymer foams and films for delivery of therapeutic agents to and through nasal, oral or vaginal mucosa and cornified or<br />

non-cornified epithelium of labia and scrotum. Polymer foams or absorbable or non-absorbable films containing a therapeutic<br />

agent incorporated therein wherein said agent is released from said foams or films upon placement of said foam or film on the<br />

surface epithelium of nasal, oral, or vaginal labia or scrotum. The foam or the film has a controllable rate of gelling, swelling and<br />

degradation and is preformed into a device or is applied as a coating to a surface of a more complex drug delivery system.<br />

(FR): L'invention concerne des mousses et des films polymères pour une distribution d'agents thérapeutiques dans et à travers la<br />

muqueuse nasale, orale ou vaginale, et l'épithélium corné ou non corné des lèvres génitales et du scrotum. L'invention concerne des<br />

mousses polymères ou des films absorbables ou non absorbables contenant un agent thérapeutique renfermé à l'intérieur de ceux-ci.<br />

L'agent thérapeutique est libéré à partir de ces mousses ou de ces films lors du placement de la mousse ou de film sur l'épithélium


de surface d'une muqueuse nasale, orale ou vaginale, sur les lèvres génitales ou sur le scrotum. La mousse ou le film présente une<br />

vitesse commandable de gélification, de gonflement et de dégradation, et est préformé pour former un dispositif, ou est appliqué en<br />

tant que revêtement sur la surface d'un système d'administration de médicament plus complexe.<br />

<strong>International</strong> search report:<br />

Received at <strong>International</strong> Bureau: 27 May 2004 (27.05.2004) [US]<br />

<strong>International</strong> preliminary examination report:<br />

Chapter II demand received: 22 March 2004 (22.03.2004)<br />

(81) Designated States:<br />

AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI,<br />

GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK,<br />

MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA,<br />

UG, UZ, VC, VN, YU, ZA, ZM, ZW<br />

European Patent Office (EPO) : AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO,<br />

SE, SI, SK, TR<br />

African Intellectual Property Organization (OAPI) : BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG<br />

African Regional Intellectual Property Organization (ARIPO) : BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW<br />

Eurasian Patent Organization (EAPO) : AM, AZ, BY, KG, KZ, MD, RU, TJ, TM

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