CV: Xavier Warot

Last Name:
WAROT
First Name:
Xavier
CV of Presenter
Job Title: Head of the Center of Phenogenomics (CPG)
Organization:
JST-ETHZ JointWS 2009
School of Life Sciences (FSV), Ecole Polytechnique Federale de Lausanne
(EPFL)
Major Field: Mouse Genetics, Mouse Phenotyping
Education: Dec. 1998: Ph.D. in molecular and cellular biology with highest honors.
Thesis director: Professor P. Chambon.
Institute of Genetics and Molecular and Cellular Biology (IGBMC).
Louis Pasteur University - Strasbourg I, Strasbourg, France.
June 1993: 'Agrégation de biochimie'
June 1992: Master’s degree in Biochemistry, Microbiology and Virology.
Denis Diderot University - Paris VII, Paris, France.
1990 – 1994: Ecole Normale Supérieure de Cachan (French ‘Grande Ecole’).
Job history: Ecole Polytechnique Fédérale de Lausanne (EPFL), School of Life Sciences (FSV).
Lausanne, Switzerland. Since June 2008.
Director of the Center of PhenoGenomics (CPG)
- Activities of the Center encompass Animal Husbandry, Transgenesis, Mouse Clinical
and Molecular Phenotyping.
Mouse Clinical Institute (MCI - ICS).
Strasbourg Illkirch, France. February 2006 – May 2008.
Director of the department of Mutagenesis and Transgenesis.
- Establishment of on demand transgenic mouse lines: projects management,
coordination of activities from construct design to first generation of animals.

CV of Presenter
F. Hoffmann-La Roche AG, Pharmaceuticals division.
JST-ETHZ JointWS 2009
Basel, Switzerland. August 2003 - January 2006.
Post doctoral Research Associate.
Department of Vascular and Metabolic Diseases, Dyslipidemia group.
- New therapeutic targets assessment: project proposal, assays development, compounds
screening.
- Study of the Liver X nuclear Receptors (LXRs). Characterization of their
transcriptional activity. Roles in lipid metabolism.
Deltagen Europe.
Strasbourg Illkirch, France. October 2001 - February 2003.
Research Scientist, project manager.
- Drug discovery: development of innovative screening strategies for the identification of
new synthetic ligands for nuclear receptors.
- Functional genomics: spatio-temporally controlled inactivation of genes encoding
nuclear receptors in the mouse with the cre/loxP system.
Institute of Genetics and Molecular and Cellular Biology (IGBMC).
Strasbourg Illkirch, France. July 2000 - September 2001.
Scientist, Dr D. Metzger’s laboratory.
Genetic engineering in the mouse.
Children's Hospital, Harvard Medical School.
Boston, USA. May 1999 - June 2000.
Post doctoral research, Dr Gabriel Corfas' laboratory, Division of Neuroscience
(EMBO fellowship).
Molecular and cellular aspects of central nervous system development and functions.
Institute of Genetics and Molecular and Cellular Biology (IGBMC).
Strasbourg Illkirch, France. September 1993 - April 1999.
Doctoral research, supervisor: Professor P. Chambon.
- Spatio-temporally controlled gene inactivation in the mouse with the Cre/loxP system.
- Study of the roles of homeotic genes during mouse embryonic development.