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Full Version - Water for Food Institute - University of Nebraska

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40<br />

GLOBAL PERSPECTIVES ON WATER FOR FOOD 2<br />

Speakers<br />

Atlin said, it is unlikely that transgenes or<br />

quantitative trait loci would have delivered<br />

similar gains without breeding advancements.<br />

The new biotechnology tools are adding onto<br />

a solid foundation <strong>of</strong> cultivar development.<br />

“We’re very concerned that the new tools that<br />

are becoming available be applied in breeding<br />

programs targeted at the poorest farmers<br />

in rainfed situations,” Atlin said. CIMMYT<br />

is sourcing and applying tools, such as<br />

improved screening approaches and<br />

phenotyping protocols, double-haploid<br />

inducers, molecular-marker technologies<br />

and breeding in<strong>for</strong>matics management.<br />

Transgenic Future<br />

CIMMYT also is involved in public-private<br />

partnerships to develop transgenes <strong>for</strong> improving<br />

drought tolerance and nitrogen-use efficiency <strong>for</strong><br />

African smallholders through the <strong>Water</strong>-Efficient<br />

Maize <strong>for</strong> Africa project with Monsanto Company<br />

and the Improved Maize <strong>for</strong> African Soils project<br />

with Pioneer. The products <strong>of</strong> these collaborations<br />

will be drought-tolerant and improved nitrogenuse<br />

transgenic varieties available to African<br />

smallholders under humanitarian licensing<br />

and market segmentation arrangements.<br />

Deployment <strong>of</strong> transgenics in developing countries<br />

requires $25 million to $100 million and at least<br />

12 years to make it to a farmer’s field, Atlin<br />

said. Few African countries have a regulatory<br />

framework allowing them to accept transgenic<br />

technology, and those that do rely on data from<br />

the U.S. regulatory system. “At the moment,<br />

and I believe <strong>for</strong> the <strong>for</strong>eseeable future, only<br />

transgenes that can be commercialized by a<br />

company <strong>for</strong> farmers in a developed country<br />

will be made available in developing countries.”<br />

A transgene beneficial in Africa, but detrimental<br />

to U.S. yields, most likely will not be developed<br />

<strong>for</strong> marketing.<br />

Drought tolerance in maize appears to be affected<br />

by many genetic factors, <strong>for</strong> which marker-index<br />

selection approaches are more suited. Fortunately,<br />

reduced costs <strong>for</strong> genotyping technologies are<br />

starting to allow CIMMYT and small breeding<br />

programs to apply these technologies. Nextgeneration<br />

sequencing <strong>of</strong> genome representations<br />

will make the haplotype, rather than the line,<br />

the selection unit, which will allow programs<br />

to share in<strong>for</strong>mation but not germplasm. That<br />

ability, along with other advances Atlin described,<br />

will encourage the development <strong>of</strong> “open-source”<br />

breeding, which could reduce breeding cycle times<br />

by fivefold and potentially double genetic gains.<br />

Making breeding in<strong>for</strong>matics accessible to<br />

smaller breeding programs will be critical to the<br />

success <strong>of</strong> the new breeding system. “There’s a<br />

wave <strong>of</strong> genotypic data that’s going to break<br />

over us in the next year or so,” Atlin said. “This<br />

is not the distant future. This is happening. We<br />

will have thousands <strong>of</strong> polymorphisms available<br />

to use in making selections within the next year<br />

to 18 months. We need to put the systems in place<br />

to allow us to surf this wave <strong>of</strong> in<strong>for</strong>mation.”<br />

Constraints<br />

Logistical constraints remain. Seed is expensive<br />

and difficult to produce, and many small<br />

companies in Africa cannot produce needed<br />

quantities, creating a serious logistical problem<br />

getting hybrid seeds to farmers. CIMMYT

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