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National Nutrition and HIV/AIDS Guidelines for Service Providers of ...

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Medication<br />

Purpose<br />

Recommendation/ advice<br />

Potential side effects<br />

Zidovudine/lami<br />

vudine/ Abacavir<br />

(AZT/3TC/ABC)<br />

Antiretroviral<br />

Combination<br />

On empty stomach if possible; if<br />

not, with low-fat meals<br />

Nausea, vomiting, abdominal<br />

pain, diarrhea, anorexia, fever,<br />

bone marrow suppression,<br />

anaemia, <strong>and</strong> hyperlactacemia.<br />

Zidovudine (AZT)<br />

Antiretroviral<br />

With low fat meal. Avoid alcohol.<br />

Anorexia, anaemia, nausea,<br />

vomiting, bone marrow<br />

suppression, headache, fatigue,<br />

constipation, fever dizziness,<br />

dyspnea, insomnia, muscle pain,<br />

<strong>and</strong> rash.<br />

Chloroquine<br />

Treatment <strong>of</strong><br />

Malaria<br />

With food<br />

Stomach pain, loss <strong>of</strong> appetite,<br />

nausea, vomiting. Not<br />

recommended <strong>for</strong> breastfeeding<br />

women taking high doses <strong>for</strong><br />

rheumatic diseases.<br />

Fluconazole<br />

Treatment <strong>of</strong><br />

C<strong>and</strong>ida<br />

With food<br />

Nausea, vomiting, diarrhea. Can<br />

be used during breastfeeding<br />

Isoniazid<br />

Treatment <strong>of</strong><br />

Tuberculosis<br />

1hour be<strong>for</strong>e or 2 hours after meals.<br />

May cause possible reactions with<br />

foods such as bananas, beer,<br />

avocados, liver, smoked pickled fish,<br />

yeast <strong>and</strong> yogurt.<br />

Anorexia <strong>and</strong> diarrhea.<br />

May interfere with vitamin B6<br />

metabolism, especially in adults<br />

<strong>and</strong> thus require vitamin B6<br />

supplementation. Avoid alcohol<br />

Nystatin<br />

Treatment <strong>of</strong><br />

Thrush<br />

With food<br />

Infrequent occurrence <strong>of</strong><br />

diarrhea, vomiting, nausea<br />

Quinine<br />

Treatment <strong>of</strong><br />

Malaria<br />

With food<br />

Rifampin<br />

Treatment <strong>of</strong><br />

Tuberculosis<br />

On an empty stomach 1hour be<strong>for</strong>e<br />

or 2 hours after meals. Avoid<br />

alcohol.<br />

Bright orange urine, Nausea,<br />

vomiting, diarrhea <strong>and</strong> loss <strong>of</strong><br />

appetite.<br />

Sulfadoxine <strong>and</strong><br />

Pyrimethamine<br />

(Fansidar)<br />

Treatment <strong>of</strong><br />

Malaria<br />

With food <strong>and</strong> continuous drinking<br />

<strong>of</strong> clean boiled <strong>and</strong> cooled water<br />

Nausea, vomiting, taste loss, <strong>and</strong><br />

diarrhea.<br />

Not recommended if folate<br />

deficient. Not recommended <strong>for</strong><br />

women breastfeeding.<br />

Sulfonamides:<br />

Sulfamethoxazol<br />

e,<br />

Cotrimoxazole<br />

(Bactrim®,<br />

Septra®)<br />

Antibiotic <strong>for</strong><br />

treatment <strong>of</strong><br />

pneumonia<br />

<strong>and</strong><br />

Toxoplasmosis<br />

With food <strong>and</strong> continuous drinking<br />

<strong>of</strong> clean boiled<br />

<strong>and</strong> cooled water (at least 8<br />

st<strong>and</strong>ard<br />

glasses per day)<br />

Nausea, vomiting, <strong>and</strong> abdominal<br />

pain<br />

43

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