Overview of bioengineering and hydrocephalus: 50 years in 30 ...

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Reader‐based pressure diagnostics • Many active developers, including majors Meithke • External‐power (no battery) • On‐demand measurements • Meithke SensorReservior (left) • Radionics Telesensor • Medtronic InSite • Codman (2009 patent) • H‐cubed (development stage?) • Issys (development stage?) • Alfred Mann Foundation
Diagnostics: status of systems • High value, lots of activity (including majors) • Potential payoff: cost savings for averted diagnostic procedures ($1.3B/year???) • Sensor challenges: required accuracy (mL/hr, cm H2O) pushes technology limits • Other challenges: cost, regulatory • Most require external power (MRI issues?) • Little activity on stand‐alone implants • Early detection, potential use in a smart shunt • But, must be stand‐alone with power source
Page 1 and 2: Barry Lutz, Ph.D. Research Assistan
Page 3 and 4: Shunt history: 50 years in 5 minute
Page 5 and 6: Shunt history: 50 years in 5 minute
Page 7 and 8: What can we do to really advance th
Page 9 and 10: Proximal obstruction: geometry •
Page 11 and 12: Proximal obstruction: coatings Prom
Page 13 and 14: Proximal obstruction: active method
Page 15 and 16: Obstruction: status and needs • P
Page 17 and 18: Reader‐based flow diagnostics •
Page 19 and 20: Reader‐based flow diagnostics •
Page 21: Pressure Sensor Requirements AMF mi
Page 25 and 26: Smart Shunts: Codman & Shurtleff
Page 27 and 28: Smart Shunts: Integra Lifesciences
Page 29 and 30: Smart Shunts: tube squeezer • Tub
Page 31 and 32: Advanced models of CSF dynamics •
Page 33 and 34: Summary: potential wins in next 5 y
Page 36 and 37: Needs with promise in next 3‐5 ye

Overview of bioengineering and hydrocephalus: 50 years in 30 ...

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