Overview of bioengineering and hydrocephalus: 50 years in 30 ...

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• Limited options for type of control • Nearly every device is dff differential pressure valve • Siphon‐control (add‐on or integrated) • Adjustable pressure set point (from all majors) • A few flow control valves (OSV, Diamond) • Et Extraordinary failure rates • 40% by year 1, 50% by year 2, 98% by year 10 • Obstruction is key cause: proximal (60%), valve (30%) • No sensors, no reliable failure diagnostics, no monitoring i capability
What can we do to really advance the status quo? • Methods/designs that reduce obstruction & in vitro biological models to test them • Diagnostics for shunt failure & monitoring • Smart Shunts for advanced control and diagnostics & bench models to test them (dynamic models) • Improved understanding di of the desirable control approaches (and devices to carry them out)
Page 1 and 2: Barry Lutz, Ph.D. Research Assistan
Page 3 and 4: Shunt history: 50 years in 5 minute
Page 5: Shunt history: 50 years in 5 minute
Page 9 and 10: Proximal obstruction: geometry •
Page 11 and 12: Proximal obstruction: coatings Prom
Page 13 and 14: Proximal obstruction: active method
Page 15 and 16: Obstruction: status and needs • P
Page 17 and 18: Reader‐based flow diagnostics •
Page 19 and 20: Reader‐based flow diagnostics •
Page 21 and 22: Pressure Sensor Requirements AMF mi
Page 23 and 24: Diagnostics: status of systems •
Page 25 and 26: Smart Shunts: Codman & Shurtleff
Page 27 and 28: Smart Shunts: Integra Lifesciences
Page 29 and 30: Smart Shunts: tube squeezer • Tub
Page 31 and 32: Advanced models of CSF dynamics •
Page 33 and 34: Summary: potential wins in next 5 y
Page 36 and 37: Needs with promise in next 3‐5 ye

Overview of bioengineering and hydrocephalus: 50 years in 30 ...

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