Overview of bioengineering and hydrocephalus: 50 years in 30 ...

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Early models of the CSF system • Early models: static single‐compartment • Bench testing of shunts follows similar “plumbing” approach Hakim physical model Maramou electrical model
Advanced models of CSF dynamics • Dynamic models needed to test smart shunts • e.g., R. Penn (left), A. Linninger, Dr. Bradley • ETH Zurich SmartShunt project (right) Penn group
Page 1 and 2: Barry Lutz, Ph.D. Research Assistan
Page 3 and 4: Shunt history: 50 years in 5 minute
Page 5 and 6: Shunt history: 50 years in 5 minute
Page 7 and 8: What can we do to really advance th
Page 9 and 10: Proximal obstruction: geometry •
Page 11 and 12: Proximal obstruction: coatings Prom
Page 13 and 14: Proximal obstruction: active method
Page 15 and 16: Obstruction: status and needs • P
Page 17 and 18: Reader‐based flow diagnostics •
Page 19 and 20: Reader‐based flow diagnostics •
Page 21 and 22: Pressure Sensor Requirements AMF mi
Page 23 and 24: Diagnostics: status of systems •
Page 25 and 26: Smart Shunts: Codman & Shurtleff
Page 27 and 28: Smart Shunts: Integra Lifesciences
Page 29: Smart Shunts: tube squeezer • Tub
Page 33 and 34: Summary: potential wins in next 5 y
Page 36 and 37: Needs with promise in next 3‐5 ye

Overview of bioengineering and hydrocephalus: 50 years in 30 ...

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