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IAH AC Gastrointestinal Disease

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Mucosal distress (1)<br />

• Term refers to the breakdown in the integrity of the mucosal<br />

surface so that one or more of the above mentioned functions<br />

cannot be carried out<br />

• It seems that when one mucosa is affected in one organ, all the<br />

mucosae are affected<br />

(Rosales 2004)<br />

• The result is not only local disease, but also systemic disease<br />

© <strong>IAH</strong> 2007<br />

12<br />

From modern investigation, it is becoming clearer that patients having disease in<br />

one mucosa, is probably affected in all mucosae.<br />

This comprise the so called mucosal stress syndrome, and was examined by<br />

Rosales in 2004, where he could show for instance that patients presenting with<br />

a disease process in one mucosa, such as the respiratory mucosa is also likely to<br />

suffer from GIT and vaginal symptoms.<br />

Rosales-Estrada M: Mucosal inflammation syndrome in allergic disease.<br />

Journal of Biomedical Therapy Winter 2007 : 3-5<br />

Due to the fact that the gut mucosa is so large, and relatively easily affected<br />

orally, this can form the point of entry to restore mucosal integrity in other<br />

locations as well.<br />

In many cases of immune modulation, the mucosal membrane is thus the<br />

preferable point of entry into the body.<br />

12

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