Luc De Vuyst.pdf - ICoMST Contact Point
Luc De Vuyst.pdf - ICoMST Contact Point
Luc De Vuyst.pdf - ICoMST Contact Point
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Target organs:<br />
Introduction - Probiotics<br />
Probiotics (προ βίος, pro bios, ‘for life’) are live microorganisms that, when<br />
consumed in an adequate amount as part of the food, confer a health<br />
benefit on the host (FAO/WHO, 2001).<br />
digestive tract (colon, small intestine, stomach)<br />
other sites of the body (oral cavity, urogenital tract, skin)<br />
immune system<br />
cardiovascular system<br />
Current delicate points of discussion:<br />
Site of activity (foods or drugs, prevention or curing, …)<br />
Viability (life or dead cells, alive upon ingestion, alive at the site of action, …)<br />
Amount of cells (food product) necessary to exert a specified probiotic effect<br />
Format of intake and carrier [mono- or mixed cultures, food (dairy) products,<br />
food supplements, pharmaceutical preparations, …]<br />
Requirement of oral administration for clinical efficacy<br />
<strong>De</strong> <strong>Vuyst</strong>, Avonts & Makras (2004). Woodhead Publishing, Ltd., Cambridge, UK