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Luc De Vuyst.pdf - ICoMST Contact Point

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Target organs:<br />

Introduction - Probiotics<br />

Probiotics (προ βίος, pro bios, ‘for life’) are live microorganisms that, when<br />

consumed in an adequate amount as part of the food, confer a health<br />

benefit on the host (FAO/WHO, 2001).<br />

digestive tract (colon, small intestine, stomach)<br />

other sites of the body (oral cavity, urogenital tract, skin)<br />

immune system<br />

cardiovascular system<br />

Current delicate points of discussion:<br />

Site of activity (foods or drugs, prevention or curing, …)<br />

Viability (life or dead cells, alive upon ingestion, alive at the site of action, …)<br />

Amount of cells (food product) necessary to exert a specified probiotic effect<br />

Format of intake and carrier [mono- or mixed cultures, food (dairy) products,<br />

food supplements, pharmaceutical preparations, …]<br />

Requirement of oral administration for clinical efficacy<br />

<strong>De</strong> <strong>Vuyst</strong>, Avonts & Makras (2004). Woodhead Publishing, Ltd., Cambridge, UK

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