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How to investigate Adherence to Antiretroviral Treatment ... - INRUD

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Chapter 1. Overview of Manual<br />

Table 1. <strong>Adherence</strong> Values across Countries and Facilities<br />

Median Percent Across All Facilities<br />

(Minimum facility percent- Maximum facility percent)<br />

Country Ethiopia Uganda Rwanda Kenya<br />

Indica<strong>to</strong>r<br />

Attendance, Dispensing, and Gap (N = 1,989) (N =1,695) (N =1,602) (N = 1,265)<br />

Exit Interviews (N = 565) (N = 408) (N = 285) (N = 373)<br />

Full self-reported adherence in last<br />

3 days from exit interview<br />

96.6<br />

(90–100)<br />

96.7<br />

(63–100)<br />

100<br />

(60–100)<br />

96.6<br />

(80–100)<br />

Average percent days covered by<br />

medicine dispensed<br />

95<br />

(89–99)<br />

91<br />

(77–97)<br />

97<br />

(88–100)<br />

95<br />

(53–100)<br />

Percent of patients with ≥ 30 days<br />

gap in medicines dispensed<br />

9<br />

(0–33)<br />

18<br />

(0–42)<br />

2<br />

(0–12)<br />

16<br />

(0–60)<br />

Percent of patients attending clinic<br />

appointment as scheduled<br />

72<br />

(58–99)<br />

78<br />

(15–100)<br />

92<br />

(38–100)<br />

77<br />

(46–96)<br />

Percent of patients attending clinic<br />

within three days of appointment<br />

N/A = Data not collected<br />

87<br />

(72–99)<br />

80<br />

(20–100)<br />

96<br />

(67–100)<br />

N/A<br />

Usefulness of Pill Counts and Self-Report in Clinic Notes<br />

Overall, only 15 percent of 6,551 patient records included a pill count (table 4). Therefore,<br />

calculating adherence measures based on pill counts in medical and pharmacy records does<br />

not appear <strong>to</strong> be widely applicable.<br />

More records included a self-report adherence measure (45 percent overall), although this<br />

measure was infrequently recorded in Rwanda (10 percent). <strong>How</strong>ever, the methods used <strong>to</strong><br />

derive these self-report measures varied, which makes comparisons problematic. In Ethiopia,<br />

for example, the method of recording self-reported adherence was <strong>to</strong> use a “G” (good) <strong>to</strong><br />

indicate better than 95 percent adherence, an “F” (fair) for 85–95 percent or a “P” (poor) for<br />

less than 85 percent. Of the 83 percent of records that included a self-report measure, 96<br />

percent were rated “good.”<br />

Table 2. Number of Records with Pill Counts and Self Reports<br />

Ethiopia Uganda Rwanda Kenya Total<br />

Number of records<br />

examined 1,989 1,695 1,602 1,265 6,551<br />

Percent of records with pill<br />

counts 0 9 44 12 15<br />

Percent of records with<br />

self-reports 83 33 10 4 45<br />

5

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