How to investigate Adherence to Antiretroviral Treatment ... - INRUD
How to investigate Adherence to Antiretroviral Treatment ... - INRUD
How to investigate Adherence to Antiretroviral Treatment ... - INRUD
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<strong>How</strong> <strong>to</strong> Investigate <strong>Adherence</strong> <strong>to</strong> <strong>Antiretroviral</strong> <strong>Treatment</strong> in Health Facilities: <strong>Adherence</strong> Indica<strong>to</strong>rs<br />
The Facility Interview Form<br />
Facility Level Indica<strong>to</strong>rs<br />
Several indica<strong>to</strong>rs gather data about the infrastructure at each health facility. These include<br />
the presence or absence of a private space for counselling and a labora<strong>to</strong>ry for CD4 or viral<br />
load testing. In addition, since consistent availability of medicines is a key determinant of<br />
adherence, several indica<strong>to</strong>rs measure the current and recent availability of ARVs and other<br />
key medicines <strong>to</strong> treat or prevent HIV-associated illnesses. The way <strong>to</strong> do this is <strong>to</strong> interview<br />
the facility manager and pharmacist, visit the pharmacy, and look at the attendance register, if<br />
available, and fill in the facility data collection form<br />
Preparing for the Facility Interview<br />
Before carrying out the interview, it is necessary <strong>to</strong> compile three lists of medicines and<br />
doses, each with up <strong>to</strong> 10 medicines and formulations—<br />
• Key ARV medicine for adults with dose and formulation<br />
• Key ARV medicine for children with dose and formulation<br />
• Key non-ARV medicines that should be present in every facility<br />
For the ARV medicines, decisions have <strong>to</strong> be made on which medicines should be present in<br />
all clinics. Therefore, first-line treatments should be included. Second-line medicines should<br />
only be included if all facilities are expected <strong>to</strong> s<strong>to</strong>ck them. The paediatric list should only be<br />
filled in if the clinic treats children with ARVs.<br />
Sample lists are included here in tables 10–12. They should be adapted <strong>to</strong> local conditions.<br />
Table 10. Sample List of Needed Adult ARVs<br />
Adults ARV First-Line Drug<br />
1 Lamivudine 150 mg tab 3TC<br />
2 Stavudine 40 mg D4T<br />
3 Stavudine 30 mg D4T<br />
4 Nevirapine 200 mg NVP<br />
5 Efavirenz 200 mg EFV<br />
6 Efavirenz 600 mg EFV<br />
Abbreviation<br />
7 ZDV+3TC 450 mg ZDV, 3TC<br />
8<br />
9<br />
10<br />
44