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Data integration in microbial genomics ... - Jacobs University

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52 3. CD<strong>in</strong>Fusion<br />

and upload it with the Tomcat manager. Further <strong>in</strong>stallation details<br />

can be found <strong>in</strong> the README.txt file that is <strong>in</strong>cluded <strong>in</strong> the source<br />

bundle and that is also available <strong>in</strong> the documentation section of the<br />

CD<strong>in</strong>Fusion web page. On some platforms the CATALINA HOME<br />

environment variable needs to be set, <strong>in</strong> order for CD<strong>in</strong>Fusion to write<br />

and read files. Relative to the path specified, CD<strong>in</strong>Fusion will create<br />

a “data” folder, where temporary files will be saved. The application<br />

has been tested on Debian GNU L<strong>in</strong>ux <strong>in</strong>stallations, but should be<br />

platform-<strong>in</strong>dependent and run on all platforms that support Java and<br />

Apache Tomcat <strong>in</strong>stallation such as W<strong>in</strong>dows TM or MAC OS TM .<br />

Availability and Future Directions<br />

The public <strong>in</strong>stallation of CD<strong>in</strong>Fusion is hosted and ma<strong>in</strong>ta<strong>in</strong>ed at the<br />

Microbial Genomics and Bio<strong>in</strong>formatics Group (MGG) of the Max<br />

Planck Institute of Mar<strong>in</strong>e Microbiology Bremen and accessible under:<br />

http://www.megx.net/cd<strong>in</strong>fusion. The source code is available<br />

under GNU LGPL 3 and deposited <strong>in</strong> a public repository: http:<br />

//code.google.com/p/cd<strong>in</strong>fusion.<br />

As open source software it is the <strong>in</strong>tention of the MGG to support this<br />

software well <strong>in</strong>to the future. Currently CD<strong>in</strong>Fusion supports submission<br />

of CD enriched sequence data to the INSDC us<strong>in</strong>g Sequ<strong>in</strong> and<br />

tbl2asn for large data sets. Support for <strong>in</strong>stallations outside the MPI<br />

cannot be granted. The direct submission to EMBL/ENA and DDBJ<br />

is planned. Furthermore the <strong><strong>in</strong>tegration</strong> of GCDML [Kottmann et al.,<br />

2008] as an exchange format would be advantageous. The GSC and<br />

life science community is encouraged to download the source code and<br />

to modify and extend the software to make it even more useful.<br />

Acknowledgments Thanks to S. Emil Ruff and the Geotechnologien<br />

project COMET/MUMM II (03G0608A, BMBF) for provid<strong>in</strong>g<br />

unpublished data and for the beta-test<strong>in</strong>g. Thanks to Michael Richter<br />

for genome data and beta-test<strong>in</strong>g. Thanks to Rudolf Amann, Bernhard<br />

Fuchs and Hanno Teel<strong>in</strong>g for the MIMAS data. Thanks to Jens Harder,<br />

Richard Hahnke and the M.Sc. Mar<strong>in</strong>e Microbiology (MarMic) class<br />

of 2014 for data and beta-test<strong>in</strong>g.

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