Data integration in microbial genomics ... - Jacobs University
Data integration in microbial genomics ... - Jacobs University
Data integration in microbial genomics ... - Jacobs University
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Contents<br />
1 Introduction 1<br />
1.1 From data to knowledge . . . . . . . . . . . . . . . . . . . . 1<br />
1.2 Relevance of microbiology . . . . . . . . . . . . . . . . . . 5<br />
1.3 The primary data source . . . . . . . . . . . . . . . . . . . 7<br />
1.4 Exponential sequence data growth . . . . . . . . . . . . . 10<br />
1.5 Importance of contextual data . . . . . . . . . . . . . . . . 11<br />
1.6 Research aims and motivation . . . . . . . . . . . . . . . . 15<br />
1.7 Overall thesis structure . . . . . . . . . . . . . . . . . . . . 15<br />
1.8 Publication overview . . . . . . . . . . . . . . . . . . . . . . 16<br />
2 MetaBar 21<br />
2.1 Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21<br />
2.2 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . 22<br />
2.3 Implementation . . . . . . . . . . . . . . . . . . . . . . . . . 26<br />
2.4 Results . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27<br />
2.5 Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30<br />
2.6 Conclusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35<br />
3 CD<strong>in</strong>Fusion 39<br />
3.1 Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39<br />
3.2 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . 40<br />
3.3 Results . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43<br />
3.4 Design and Implementation . . . . . . . . . . . . . . . . . 47<br />
4 MIMARKS 55<br />
4.1 Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56