Complete - College of Medicine - University of Illinois at Urbana ...
Complete - College of Medicine - University of Illinois at Urbana ...
Complete - College of Medicine - University of Illinois at Urbana ...
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Helping Diabetic P<strong>at</strong>ients<br />
Michael Jakoby, M.D., M.A., and Donald Layman, Ph.D.<br />
Dr. Layman and Dr. Jakoby have<br />
established a study to examine the<br />
health benefits <strong>of</strong> high-protein diets<br />
for Type 2 diabetes p<strong>at</strong>ients.<br />
The connection between good nutrition and good health is<br />
no secret, but unlocking the mystery <strong>of</strong> which foods provide<br />
the gre<strong>at</strong>est health benefits for each person requires a<br />
special partnership.<br />
Donald Layman, Ph.D., pr<strong>of</strong>essor <strong>of</strong> nutrition, and Michael<br />
Jakoby, M.D., M.A., clinical assistant pr<strong>of</strong>essor <strong>of</strong> internal<br />
medicine, provide the expertise to establish such connections.<br />
And their collabor<strong>at</strong>ion looks to shed light on the health<br />
benefits <strong>of</strong> protein-rich diets for diabetic p<strong>at</strong>ients.<br />
Dr. Layman’s recent research has focused on how and why<br />
e<strong>at</strong>ing more high-quality protein aids weight loss. His findings<br />
suggest th<strong>at</strong> such a diet increases the amount <strong>of</strong> leucine, an<br />
amino acid, in the diet, which is important for maintaining<br />
muscle mass and reducing body f<strong>at</strong> during weight loss. In<br />
addition, he found th<strong>at</strong> a high-protein diet resulted in more<br />
stable glucose levels, reduced insulin response following meals,<br />
and decreased triglyceride levels in study participants – all <strong>of</strong><br />
which have important implic<strong>at</strong>ions not just for weight loss<br />
p<strong>at</strong>ients but for diabetic p<strong>at</strong>ients as well.<br />
And th<strong>at</strong>’s where the collabor<strong>at</strong>ion comes in. Dr. Layman and<br />
Dr. Jakoby have established a study to examine the health<br />
benefits <strong>of</strong> such a high-protein diet for Type 2 diabetes<br />
p<strong>at</strong>ients. “In this type <strong>of</strong> study, subjects need physician<br />
supervision because diet changes may also require changes<br />
in medic<strong>at</strong>ions,” says Dr. Layman. “As a clinician, Dr. Jakoby<br />
brings the expertise <strong>of</strong> the endocrinologist as well as the<br />
direct p<strong>at</strong>ient contact th<strong>at</strong> is essential for this research.”<br />
Initial findings <strong>of</strong> their study look promising. “On a highcarbohydr<strong>at</strong>e<br />
diet, the body’s levels <strong>of</strong> glucose and insulin<br />
swing dram<strong>at</strong>ically,” Layman says. “On a high-protein diet,<br />
blood sugar levels tend to be more constant because amino<br />
acids stimul<strong>at</strong>e the body to make its own glucose. The body<br />
makes glucose from protein to use as energy, but it does it<br />
slowly throughout the day. It is a continuous process. The<br />
demands on insulin are much less after a meal with a lower<br />
r<strong>at</strong>io <strong>of</strong> carbohydr<strong>at</strong>e to protein.”<br />
Dr. Jakoby sees from his p<strong>at</strong>ients how this research theory<br />
works in practice. “The blood glucose control <strong>of</strong> study<br />
participants has improved significantly. Self-monitored<br />
blood glucose levels have fallen into the range considered<br />
desirable by the American Diabetes Associ<strong>at</strong>ion.”<br />
6 T h e P o w e r o f C o l l a b o r a t i o n