02.04.2014 Views

Complete - College of Medicine - University of Illinois at Urbana ...

Complete - College of Medicine - University of Illinois at Urbana ...

Complete - College of Medicine - University of Illinois at Urbana ...

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

Helping Diabetic P<strong>at</strong>ients<br />

Michael Jakoby, M.D., M.A., and Donald Layman, Ph.D.<br />

Dr. Layman and Dr. Jakoby have<br />

established a study to examine the<br />

health benefits <strong>of</strong> high-protein diets<br />

for Type 2 diabetes p<strong>at</strong>ients.<br />

The connection between good nutrition and good health is<br />

no secret, but unlocking the mystery <strong>of</strong> which foods provide<br />

the gre<strong>at</strong>est health benefits for each person requires a<br />

special partnership.<br />

Donald Layman, Ph.D., pr<strong>of</strong>essor <strong>of</strong> nutrition, and Michael<br />

Jakoby, M.D., M.A., clinical assistant pr<strong>of</strong>essor <strong>of</strong> internal<br />

medicine, provide the expertise to establish such connections.<br />

And their collabor<strong>at</strong>ion looks to shed light on the health<br />

benefits <strong>of</strong> protein-rich diets for diabetic p<strong>at</strong>ients.<br />

Dr. Layman’s recent research has focused on how and why<br />

e<strong>at</strong>ing more high-quality protein aids weight loss. His findings<br />

suggest th<strong>at</strong> such a diet increases the amount <strong>of</strong> leucine, an<br />

amino acid, in the diet, which is important for maintaining<br />

muscle mass and reducing body f<strong>at</strong> during weight loss. In<br />

addition, he found th<strong>at</strong> a high-protein diet resulted in more<br />

stable glucose levels, reduced insulin response following meals,<br />

and decreased triglyceride levels in study participants – all <strong>of</strong><br />

which have important implic<strong>at</strong>ions not just for weight loss<br />

p<strong>at</strong>ients but for diabetic p<strong>at</strong>ients as well.<br />

And th<strong>at</strong>’s where the collabor<strong>at</strong>ion comes in. Dr. Layman and<br />

Dr. Jakoby have established a study to examine the health<br />

benefits <strong>of</strong> such a high-protein diet for Type 2 diabetes<br />

p<strong>at</strong>ients. “In this type <strong>of</strong> study, subjects need physician<br />

supervision because diet changes may also require changes<br />

in medic<strong>at</strong>ions,” says Dr. Layman. “As a clinician, Dr. Jakoby<br />

brings the expertise <strong>of</strong> the endocrinologist as well as the<br />

direct p<strong>at</strong>ient contact th<strong>at</strong> is essential for this research.”<br />

Initial findings <strong>of</strong> their study look promising. “On a highcarbohydr<strong>at</strong>e<br />

diet, the body’s levels <strong>of</strong> glucose and insulin<br />

swing dram<strong>at</strong>ically,” Layman says. “On a high-protein diet,<br />

blood sugar levels tend to be more constant because amino<br />

acids stimul<strong>at</strong>e the body to make its own glucose. The body<br />

makes glucose from protein to use as energy, but it does it<br />

slowly throughout the day. It is a continuous process. The<br />

demands on insulin are much less after a meal with a lower<br />

r<strong>at</strong>io <strong>of</strong> carbohydr<strong>at</strong>e to protein.”<br />

Dr. Jakoby sees from his p<strong>at</strong>ients how this research theory<br />

works in practice. “The blood glucose control <strong>of</strong> study<br />

participants has improved significantly. Self-monitored<br />

blood glucose levels have fallen into the range considered<br />

desirable by the American Diabetes Associ<strong>at</strong>ion.”<br />

6 T h e P o w e r o f C o l l a b o r a t i o n

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!