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Eisai Co., Ltd. Annual Report 2001 - Eisai GmbH

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2<br />

TO OUR SHAREHOLDERS<br />

In fiscal 2000, which ended March 31, <strong>2001</strong>, <strong>Eisai</strong> achieved record<br />

consolidated results, due to the continued sales growth in global<br />

markets of the Alzheimer’s disease treatment Aricept, and the proton<br />

pump inhibitor Aciphex/Pariet. This achievement reflects the ongoing<br />

support of shareholders and other stakeholders in the <strong>Co</strong>mpany. On<br />

behalf of everyone at <strong>Eisai</strong>, we would like to express our sincerest<br />

appreciation.<br />

<strong>Eisai</strong> sees our ultimate goal as satisfying customers—the patients<br />

using our products—and our fundamental mission as determining<br />

effective ways and allocating management resources effectively to<br />

achieve this goal. Accordingly, we focus on developing pharmaceuticals<br />

that satisfy unmet medical needs and enhance the quality of life<br />

of patients worldwide. We also observe the highest standards of<br />

quality and aim to provide information in easily accessible formats.<br />

With Aricept, we have established a safe and effective course of<br />

treatment for Alzheimer’s disease. Aricept has received approval in<br />

78 countries and is playing a crucial role in efforts to treat patients<br />

with mild to moderate Alzheimer's disease. We are also developing an<br />

agent for treating sepsis, E5564, which is produced using proprietary<br />

synthesis technologies. In the area of cancer research, we are pursuing<br />

the development of substances with various mechanisms—such as<br />

E7070 that affects the cell cycle at the G1 stage, tubulin antagonists<br />

and antiangiogenics, which inhibit blood vessel formation—that offer<br />

new hope for treating this disease. In the field of neurology, which we<br />

have positioned as our most important strategic therapeutic area, we<br />

are working toward the development of effective treatments for<br />

neurogenerative disorders including multiple sclerosis and other<br />

illnesses. Substances currently in development include the serotonin<br />

receptor antagonist E2101, and the amino-3-hydroxy-5-methyl-4isoxazolepropionate<br />

(AMPA) type glutamate receptor antagonist<br />

E2007, for which we have received a concept patent for the inhibition<br />

of neural dysfunction associated with multiple selerosis. Our research<br />

in the neurology area also includes the development of additional<br />

indications for Aricept.<br />

<strong>Eisai</strong> <strong>Annual</strong> <strong>Report</strong> <strong>2001</strong>

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