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Testing and quality

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SULZER ANALOGY<br />

<strong>Testing</strong> poisons<br />

In the plant world, there are numerous poisons, which,<br />

when consumed, can lead to serious problems or even<br />

death for human beings. People always have to try<br />

something out first in order to determine whether it is<br />

poisonous or not. So how do animals know which plants<br />

to beware of <strong>and</strong> which are beneficial?<br />

Structural formula of<br />

the alkaloid morphine,<br />

which Friedrich Wilhelm<br />

Sertürner extracted<br />

from the opium poppy<br />

in pure form in 1806.<br />

The struggle for survival in the natural<br />

world takes place not only between<br />

hunting lions <strong>and</strong> fleeing gazelles. Even<br />

the apparently peaceful coexistence<br />

between plants <strong>and</strong> animals is an incessant<br />

battle with the aim of surviving<br />

long enough to pass on one’s own genes<br />

to the next generation. As plants are<br />

unable to flee their predators, they have<br />

to defend themselves from the hungry<br />

mouths of animals in other ways. Spines,<br />

thorns, <strong>and</strong> bristly hairs offer mechanical<br />

protection. Unpleasant odors may also<br />

discourage consumption. The most effective<br />

defenses, however, are plant toxins<br />

that punish the “attacker” with physical<br />

problems or even death.<br />

It’s purely the dosage that makes<br />

the poison<br />

The plant world has developed an<br />

incredible wealth of chemical defenses.<br />

Tannins are very astringent. They cause<br />

the tongue to contract, dry out the<br />

mouth <strong>and</strong> throat, <strong>and</strong> disturb digestion.<br />

The greatest poison arsenal, however,<br />

are the alkaloids, which can be found<br />

© Smellme | Dreamstime.com<br />

in 20 percent of all flowering plants.<br />

Anyone who does not regard the<br />

bitter taste as a warning will have to<br />

experience on this own body how these<br />

nerve agents work.<br />

Humans also know about these<br />

poisons—from the atropine in the<br />

deadly nightshade <strong>and</strong> the quinine in<br />

cinchona bark to the nicotine in tobacco<br />

<strong>and</strong> the caffeine in coffee. Like almost<br />

any poison, alkaloids are digestible in<br />

small dosages, <strong>and</strong> they can have a<br />

stimulating or intoxicating effect. Both<br />

humans <strong>and</strong> animals have learned that<br />

low quantities of alkaloids only damage<br />

microbes <strong>and</strong> insects, <strong>and</strong> thereby<br />

provide the body with some protection<br />

against certain infections <strong>and</strong> pests.<br />

How do animals know what is poisonous?<br />

In order to avoid risks, the<br />

p<strong>and</strong>a bear restricts itself to harmless<br />

bamboo plants—with the disadvantage<br />

that it has to consume enormous quantities<br />

of this plant, which is low in nutrition.<br />

The rat has a very different strategy.<br />

It is an omnivore <strong>and</strong> has conquered the<br />

entire world thanks to its flexibility. As<br />

poisons lurk everywhere, the rat is very<br />

mistrustful of new things. If it finds an<br />

unfamiliar food source, it only eats a<br />

mini-portion at first. Only if it does<br />

not suffer any adverse reaction does it<br />

consume the new discovery in larger<br />

quantities. Moreover, if it sees that other<br />

rats are eating a new food without any<br />

Black howler monkey: Consumes unknown plant material only in small<br />

quantities in order to avoid a possible poisoning.<br />

problem, the rat knows that it can also<br />

eat the new food.<br />

Poison training course for rat<br />

embryos<br />

The poison training course for rats starts<br />

in the womb, where the embryo<br />

develops aversions to noxious smells<br />

<strong>and</strong> a preference for safe tastes. In<br />

mammals, young animals learn with<br />

their mother’s milk how good food<br />

smells <strong>and</strong> tastes. Moreover, when the<br />

baby animal takes its food from its<br />

mother’s mouth, this is not simply convenience,<br />

but vital training of the highest<br />

<strong>quality</strong>.<br />

Anyone who is mainly surrounded by<br />

poisonous leaves, such as the howler<br />

monkeys in the coastal forest of Costa<br />

Rica, has to come up with a particularly<br />

subtle feeding strategy. The more<br />

abundant a type of tree, the more is it<br />

avoided by the apes—because the only<br />

plants that can thrive are those that are<br />

inedible for herbivores. If a tree is judged<br />

acceptable, the animals seek out the<br />

youngest <strong>and</strong> smallest leaves—<strong>and</strong> if<br />

the plant nevertheless produces toxins,<br />

these would initially only be present in<br />

small amounts in fresh plant material.<br />

Furthermore, the howler monkeys only<br />

eat the stem of the leaf, thereby keeping<br />

to the part of the plant with the lowest<br />

toxic content.<br />

Herbert Cerutti<br />

4331 Sulzer Technical Review 1/2011 | 17

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