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UNIVERSITÀ DEGLI STUDI DI TRIESTE - OpenstarTs - Università ...

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Conclusions and future developments<br />

Conclusions and future developments<br />

The measurement of respiratory mechanics is essential in intensive care respiratory<br />

medicine. Nevertheless, the respiratory mechanism is rarely measured in the ventilatordependent<br />

patients to the belief that these measures are even more difficult to obtain and to<br />

interpret and unreliable, especially in the case of high-frequency percussive ventilation, on<br />

which there are few studies .<br />

In this work the basis of the characterization of high-frequency percussive ventilator were<br />

laid, identifying the characteristics of elastic and resistive load.<br />

The ventilation conditions currently used in medicine mostly include the adjustment of the<br />

frequency of percussion and pressure peak, and then the work has been addressed towards the<br />

analysis of these variables, proving to be adequate to justify the positive results obtained in<br />

intensive care, in the treatment of patients with certain respiratory problems.<br />

An important result is the possibility of obtaining estimates of respiratory parameters<br />

which, within acceptable limits of error, provide the evolutionary trend of respiratorymechanical<br />

characteristics of a patient independently of the frequency of percussion.<br />

Therefore, it is not necessary to replace the percussive ventilator with a conventional for the<br />

measure of those parameters. This allow to follow the temporal evolution of the resistive and<br />

viscoelastic conditions, the latter particularly dependent upon removal of bronchial secretions.<br />

The high-frequency percussive ventilation combines together two complementary<br />

mechanisms: the high oscillation frequency (diffusive behavior) and pressure controlled<br />

ventilation (convective behavior). The prevalence of either depends on the mechanical<br />

impedance characteristics, but their combined action leads to a sufficient exchange of<br />

pulmonary gases in patient and in all situations.<br />

From the obtained results we can deduce that the VDR-4 is a versatile ventilator which<br />

provides adequate ventilation at all load conditions, as a result of the use of a Venturi type<br />

device, which allows the patient to enter at any stage of ventilation with his spontaneous<br />

93

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