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Link to our lab as a pdf - College of Science - Marshall University

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Post-Lab Questions<br />

Short Answer<br />

1. Which woman could be Louise Mondelo?<br />

2. Could the driver <strong>of</strong> the car be the mother <strong>of</strong> the two children in the car?<br />

3. Of the known samples, who could have been Jan’s parents? Wally’s?<br />

4. Of the known samples, whose DNA could be on the firewood?<br />

5. Of the known samples, whose flesh could have been left on the fireplace?<br />

6. Is it e<strong>as</strong>ier <strong>to</strong> prove that two DNA samples match or do not match?<br />

7. Is it e<strong>as</strong>ier <strong>to</strong> prove guilt or innocence using DNA?<br />

8. Given that there are only 8,300 people in the county where Highland Park is, how many people in that<br />

county would you expect <strong>to</strong> find with the same genotype <strong>as</strong> each <strong>of</strong> the unknowns?<br />

9. Assuming an STR with 5 alleles (ignoring the very rare ‘<strong>of</strong>f ladder’ alleles), how many genotypes exist?<br />

10. Using the information from #9 above, and <strong>as</strong>suming that every STR h<strong>as</strong> 5 alleles, on average, how many<br />

STRs are needed <strong>to</strong> expect <strong>to</strong> find only one person <strong>of</strong> a given genotype in a population <strong>of</strong> 300 million?<br />

30<br />

The Mystery <strong>of</strong> Lyle and Louise

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