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twrama 1990_final oc.. - AMA WA

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TOMORROW’S HEALTH<br />

in screening the at-risk population for neurodegenerative<br />

disease such as Alzheimer’s and Parkinson’s disease and<br />

instituting therapy before the development of symptoms.<br />

Inflammatory diseases of the CNS such as multiple sclerosis<br />

will be more accurately defined and categorised at a much<br />

earlier stage. Cancer patients’ chemotherapy efficacy will<br />

be determined after a single dose of the drug by the ability<br />

to determine with PET/MRI whether the drug attaches to<br />

the tumor receptors and will be effective – personalising the<br />

treatment to the individual patient.<br />

MRI contrast media linked to specific antibodies will<br />

lead to definitive diagnoses without the need for invasive<br />

pr<strong>oc</strong>edure in many organs with clinical and radiological<br />

features of a disease.<br />

High field MRI spectroscopy will supplement the imaging<br />

data and pinpoint metabolic pathways, which are deranged<br />

in various disease pr<strong>oc</strong>esses in all parts of the body to both<br />

confirm the diagnosis and aid therapeutic decisions.<br />

Angiographic assessment of very small vessels including<br />

coronary artery branches, renal artery branches, intracranial<br />

artery branches and digital artery branches will be non<br />

invasive.<br />

Imaging requests and patient appointments will be<br />

electronic and clinical details will be available to the<br />

radiologist via e-health links. This will ensure that an<br />

appropriate imaging study is carried out to answer the<br />

clinical question asked. All imaging will be digital and placed<br />

on a central server in a secure l<strong>oc</strong>ation (e.g. the Health<br />

Department) regardless of where the imaging is carried out.<br />

All imaging providers will be linked to the central server to<br />

download the imaging data and the report, with immediate<br />

access of this data when a patient provides the authority to do<br />

so. The federal e-health program will in due course allow this<br />

to come about.<br />

All metropolitan, remote and rural hospitals will be linked<br />

via PACS and e-health consultation with specific imaging<br />

specialists for an opinion on difficult cases. This opinion may<br />

be sought at a state, national or indeed at an international<br />

level. This will ensure that there is ‘value added’ to the<br />

specialist referrer in the opinion offered.<br />

Interventional radiology: Image-guided<br />

interventional pr<strong>oc</strong>edures and developments in techniques will<br />

further reduce the need for surgical interventions. Ablation<br />

of solid tumors will be more effective than present with lasers<br />

of specific wavelengths for application in the thorax, liver,<br />

kidneys and osseous structures. Image-guided delivery of<br />

chemotherapeutic agents, via direct placement (as in vertebrae,<br />

liver and kidneys and other solid organs) or via micro catheters<br />

as in brain lesions, will increase the efficacy of these agents<br />

minimising systemic side effects.<br />

Stent placement in blood<br />

vessels, ducts and hollow<br />

viscera will be much<br />

more accurate with<br />

‘CT/angiography’ as<br />

currently employed About 15 per cent of the<br />

in intracranial<br />

health care budget is<br />

vascular<br />

interventions.<br />

consumed by imaging, of<br />

Developments<br />

which about 20 per cent is<br />

are underway<br />

to manufacture<br />

inappropriate<br />

biodegradable and<br />

bioactive stents, ass<strong>oc</strong>iated<br />

with fewer long-term<br />

complications.<br />

Stroke management has advanced<br />

significantly in the last decade or so with the use of thrombolytic<br />

agents-administered IV. Dedicated stroke units with 24/7<br />

service and rapid clinical and imaging triage will be the norm.<br />

Patients with large clot burdens will be managed with both<br />

IV thrombolytics and direct clot retrieval by highly-trained<br />

interventional neuroradiologists. This model is in operation at<br />

several l<strong>oc</strong>ations worldwide and has a very significant benefit in<br />

patient outcomes. Developments in equipment and devices for<br />

intracranial aneurysm management, ruptured and unruptured,<br />

is leading to an ever-increasing <strong>oc</strong>clusion of these lesions via<br />

interventional means. Treatment of intracranial vessel stenosis and<br />

acute <strong>oc</strong>clusions is a challenge, but there is progress towards the<br />

design of appropriate stents.<br />

Research and training: About 15 per cent of<br />

the health care budget is consumed by imaging, of which<br />

about 20 per cent is inappropriate. In part, this is related<br />

to poor communication between referring clinicians and<br />

radiologists and in part, lack of understanding on the part<br />

of the requesting clinician as to which imaging modality is<br />

best suited to answer a particular clinical question. Medical<br />

students need to be exposed to imaging paradigms to<br />

ensure appropriate utilisation of imaging. This can be easily<br />

achieved via a Chair in imaging, which sadly is lacking in<br />

Western Australia. However, this position will come about.<br />

An academic position will stimulate research at a multidisciplinary<br />

clinical, medical student and basic science level<br />

with obvious benefit for the patients of this state.<br />

The molecule is in sight, but it is not the end game. ■<br />

An <strong>AMA</strong> (<strong>WA</strong>) Council Member, Professor Mark Khangure<br />

is a respected clinical neuroradiologist working with SKG<br />

Radiology. He was previously head of Imaging Services at<br />

Royal Perth Hospital.<br />

October MEDICUS 39

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