twrama 1990_final oc.. - AMA WA
twrama 1990_final oc.. - AMA WA
twrama 1990_final oc.. - AMA WA
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SNIPPET<br />
BREAST CANCER SURVIVAL<br />
IMPROVING<br />
Survival rates for breast cancer nationally are<br />
improving. However, 37 Australian women are<br />
diagnosed with breast cancer each day, according to a<br />
report released today by the Australian Institute of Health<br />
and Welfare (AIHW) and Cancer Australia.<br />
The report, Breast Cancer in Australia: An Overview<br />
shows the number of new breast cancer cases more than<br />
doubled from around 5300 to 13,600 cases between 1982<br />
and 2008.<br />
“There was a sharp increase in the incidence rate of<br />
breast cancer between <strong>1990</strong> and 1995, after which the rate<br />
has been stable,” said AIHW spokesperson Anne Bech.<br />
“The sharp increase in the incidence rate in the early<br />
<strong>1990</strong>s was most likely due to the introduction of the<br />
national breast cancer screening program in 1991.”<br />
Breast cancer is the most common cancer in Australian<br />
women and the majority of cases (69 per cent) are<br />
diagnosed in women aged 40-69.<br />
“The number of women diagnosed with breast<br />
cancer is expected to rise in the future due to the ageing<br />
population. Our projections indicate that in 2020 about<br />
17,200 new breast cancers will be diagnosed in Australia.<br />
This would equate to 47 women being diagnosed every<br />
day,” Ms Bech said.<br />
“Importantly, the report also shows that survival from<br />
breast cancer continues to improve in Australia, with these<br />
improvements due to both earlier diagnosis and better<br />
treatments,” Cancer Australia CEO Dr Helen Zorbas<br />
said.<br />
Between the periods 1982-1987 and 2006-2010, fiveyear<br />
relative survival from breast cancer increased from 72<br />
per cent to 89 per cent.<br />
“Although survival rates are improving, the impact on<br />
the lives of Australian women is high with seven women<br />
still dying each day from breast cancer,” Dr Zorbas said.<br />
SCAR TREATMENT TRIAL<br />
VOLUNTEERS SOUGHT<br />
Researchers from The University of Western Australia’s<br />
Burn Injury Research Unit are seeking people with keloid<br />
scarring to trial a new treatment that could halt growth of the<br />
scars while avoiding the side effects of current treatment.<br />
The tumour-like scars are benign but uncontrollable growths<br />
that can develop at the site of burn wounds or after simple<br />
injuries such as scratches, insect stings, ear piercings or needle<br />
injections.<br />
Researcher Patricia Danielsen, a visiting Danish<br />
dermatologist-in-training and visiting research fellow at the<br />
Burn Injury Research Unit headed by U<strong>WA</strong> Winthrop Professor<br />
Fiona Wood, said it was not clear what caused keloid scarring.<br />
However, it was more likely to affect people with darker skin<br />
pigmentation, seemed to be more common amongst women –<br />
perhaps because of their higher incidence of pierced ears - and<br />
typically affected people aged between 10 and 30-40 years of age.<br />
“You have some kind of trauma and the skin is repaired but it<br />
continues to build up and grow beyond the initial boundaries of<br />
the wound,” Dr Danielsen said.<br />
“Some people end up with quite a bulky tumour of scar<br />
tissue and have a lot of serious symptoms. They can have pain<br />
and itching and there’s quite a heavy psychological side to it, but<br />
they might not seek help because they don’t know we might have<br />
an alternative treatment for them, or they may have just given up.”<br />
Dr Danielsen said current treatment involved surgically<br />
removing the keloid scar, followed by corticosteroid injections<br />
into the wound. Surgery alone was never enough because the<br />
keloids grew back, often bigger than before. Growth-inhibiting<br />
adjuvant drug therapy was essential but the use of corticosteroid<br />
injections came with the risk of side effects.<br />
Instead, U<strong>WA</strong> researchers will trial the drug Verapamil,<br />
better known for treating heart complaints and migraines but<br />
which may also help to treat scar tissue.<br />
“Verapamil is very well known – we know all the side effects<br />
and they’re not too serious,” Dr Danielsen said. “The aim of the<br />
study is to see if the treatment is just as good as the traditional<br />
treatment but hopefully with fewer side effects.”<br />
During the year-long randomised trial funded by the Fiona<br />
Wood Foundation, participants will have their keloid scars<br />
removed under l<strong>oc</strong>al anaesthetic by Professor Wood or Professor<br />
Suzanne Rea. At regular intervals over the following year,<br />
they will be treated with injections of Verapamil and closely<br />
monitored for signs of re-growth.<br />
“We can’t offer this treatment yet as a standard treatment but<br />
it is a well-known and widely known medication,” Dr Danielsen<br />
said. “We need first to know how it goes, with long enough<br />
follow-up time to be certain the keloid scars won’t regrow.”<br />
Researchers need about 30 participants aged over 18. People<br />
interested in taking part or who want to find out more can<br />
contact the Burn Injuries Research Unit on 6488 8133 or visit<br />
www.fionawoodfoundation.com.<br />
THE 2012 WESFARMERS’ HARRY PERKINS ORATION<br />
If researchers are claiming so many ‘breakthroughs’, why are so many of people still getting cancer? Are we really<br />
making progress? The answer is a definite ‘yes’. There is much hope and good news. Come to hear about the future<br />
of cancer research, new treatments and how can we work together to reduce the burden of cancer on patients and<br />
carers.<br />
The Western Australian Institute for Medical Research (<strong>WA</strong>IMR) invites you to an important oration by Professor<br />
Joseph Trapani (pictured left), who will be visiting Perth from the Peter MacCallum Cancer Institute in Melbourne.<br />
Date: 2 November, 2012 (4–5pm)<br />
Venue: The University Club of <strong>WA</strong>, Off Hackett Drive, Nedlands<br />
This year’s Wesfarmers’ Harry Perkins Oration is a not-to-be missed event for anybody in Perth who is interested in<br />
cancer research and immunotherapy. It is free, including refreshments, but registration is essential as places are limited.<br />
Please contact <strong>WA</strong>IMR on 9224.0333/9224.0324 or email margot.clarke@waimr.uwa.edu.au by 25 October 2012.<br />
October MEDICUS 41