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twrama 1990_final oc.. - AMA WA

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SNIPPET<br />

BREAST CANCER SURVIVAL<br />

IMPROVING<br />

Survival rates for breast cancer nationally are<br />

improving. However, 37 Australian women are<br />

diagnosed with breast cancer each day, according to a<br />

report released today by the Australian Institute of Health<br />

and Welfare (AIHW) and Cancer Australia.<br />

The report, Breast Cancer in Australia: An Overview<br />

shows the number of new breast cancer cases more than<br />

doubled from around 5300 to 13,600 cases between 1982<br />

and 2008.<br />

“There was a sharp increase in the incidence rate of<br />

breast cancer between <strong>1990</strong> and 1995, after which the rate<br />

has been stable,” said AIHW spokesperson Anne Bech.<br />

“The sharp increase in the incidence rate in the early<br />

<strong>1990</strong>s was most likely due to the introduction of the<br />

national breast cancer screening program in 1991.”<br />

Breast cancer is the most common cancer in Australian<br />

women and the majority of cases (69 per cent) are<br />

diagnosed in women aged 40-69.<br />

“The number of women diagnosed with breast<br />

cancer is expected to rise in the future due to the ageing<br />

population. Our projections indicate that in 2020 about<br />

17,200 new breast cancers will be diagnosed in Australia.<br />

This would equate to 47 women being diagnosed every<br />

day,” Ms Bech said.<br />

“Importantly, the report also shows that survival from<br />

breast cancer continues to improve in Australia, with these<br />

improvements due to both earlier diagnosis and better<br />

treatments,” Cancer Australia CEO Dr Helen Zorbas<br />

said.<br />

Between the periods 1982-1987 and 2006-2010, fiveyear<br />

relative survival from breast cancer increased from 72<br />

per cent to 89 per cent.<br />

“Although survival rates are improving, the impact on<br />

the lives of Australian women is high with seven women<br />

still dying each day from breast cancer,” Dr Zorbas said.<br />

SCAR TREATMENT TRIAL<br />

VOLUNTEERS SOUGHT<br />

Researchers from The University of Western Australia’s<br />

Burn Injury Research Unit are seeking people with keloid<br />

scarring to trial a new treatment that could halt growth of the<br />

scars while avoiding the side effects of current treatment.<br />

The tumour-like scars are benign but uncontrollable growths<br />

that can develop at the site of burn wounds or after simple<br />

injuries such as scratches, insect stings, ear piercings or needle<br />

injections.<br />

Researcher Patricia Danielsen, a visiting Danish<br />

dermatologist-in-training and visiting research fellow at the<br />

Burn Injury Research Unit headed by U<strong>WA</strong> Winthrop Professor<br />

Fiona Wood, said it was not clear what caused keloid scarring.<br />

However, it was more likely to affect people with darker skin<br />

pigmentation, seemed to be more common amongst women –<br />

perhaps because of their higher incidence of pierced ears - and<br />

typically affected people aged between 10 and 30-40 years of age.<br />

“You have some kind of trauma and the skin is repaired but it<br />

continues to build up and grow beyond the initial boundaries of<br />

the wound,” Dr Danielsen said.<br />

“Some people end up with quite a bulky tumour of scar<br />

tissue and have a lot of serious symptoms. They can have pain<br />

and itching and there’s quite a heavy psychological side to it, but<br />

they might not seek help because they don’t know we might have<br />

an alternative treatment for them, or they may have just given up.”<br />

Dr Danielsen said current treatment involved surgically<br />

removing the keloid scar, followed by corticosteroid injections<br />

into the wound. Surgery alone was never enough because the<br />

keloids grew back, often bigger than before. Growth-inhibiting<br />

adjuvant drug therapy was essential but the use of corticosteroid<br />

injections came with the risk of side effects.<br />

Instead, U<strong>WA</strong> researchers will trial the drug Verapamil,<br />

better known for treating heart complaints and migraines but<br />

which may also help to treat scar tissue.<br />

“Verapamil is very well known – we know all the side effects<br />

and they’re not too serious,” Dr Danielsen said. “The aim of the<br />

study is to see if the treatment is just as good as the traditional<br />

treatment but hopefully with fewer side effects.”<br />

During the year-long randomised trial funded by the Fiona<br />

Wood Foundation, participants will have their keloid scars<br />

removed under l<strong>oc</strong>al anaesthetic by Professor Wood or Professor<br />

Suzanne Rea. At regular intervals over the following year,<br />

they will be treated with injections of Verapamil and closely<br />

monitored for signs of re-growth.<br />

“We can’t offer this treatment yet as a standard treatment but<br />

it is a well-known and widely known medication,” Dr Danielsen<br />

said. “We need first to know how it goes, with long enough<br />

follow-up time to be certain the keloid scars won’t regrow.”<br />

Researchers need about 30 participants aged over 18. People<br />

interested in taking part or who want to find out more can<br />

contact the Burn Injuries Research Unit on 6488 8133 or visit<br />

www.fionawoodfoundation.com.<br />

THE 2012 WESFARMERS’ HARRY PERKINS ORATION<br />

If researchers are claiming so many ‘breakthroughs’, why are so many of people still getting cancer? Are we really<br />

making progress? The answer is a definite ‘yes’. There is much hope and good news. Come to hear about the future<br />

of cancer research, new treatments and how can we work together to reduce the burden of cancer on patients and<br />

carers.<br />

The Western Australian Institute for Medical Research (<strong>WA</strong>IMR) invites you to an important oration by Professor<br />

Joseph Trapani (pictured left), who will be visiting Perth from the Peter MacCallum Cancer Institute in Melbourne.<br />

Date: 2 November, 2012 (4–5pm)<br />

Venue: The University Club of <strong>WA</strong>, Off Hackett Drive, Nedlands<br />

This year’s Wesfarmers’ Harry Perkins Oration is a not-to-be missed event for anybody in Perth who is interested in<br />

cancer research and immunotherapy. It is free, including refreshments, but registration is essential as places are limited.<br />

Please contact <strong>WA</strong>IMR on 9224.0333/9224.0324 or email margot.clarke@waimr.uwa.edu.au by 25 October 2012.<br />

October MEDICUS 41

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