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Basic Concepts of Fluid and Electrolyte Therapy

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The external fluid <strong>and</strong> electrolyte balance between the body <strong>and</strong> its<br />

environment is defined by the intake <strong>of</strong> fluid <strong>and</strong> electrolytes versus<br />

the output from the kidneys, the gastrointestinal tract, <strong>and</strong> the skin<br />

<strong>and</strong> lungs (insensible loss). Since the external <strong>and</strong> internal balances<br />

may be disturbed by disease, it is important to underst<strong>and</strong> normal<br />

physiology in order to appreciate the disorders, which may occur in<br />

patients.<br />

External balance<br />

Values for the normal daily intake <strong>and</strong> output <strong>of</strong> fluid <strong>and</strong> electrolytes<br />

are shown in Tables 1 <strong>and</strong> 2. These are only an approximate guide <strong>and</strong><br />

may have to be modified in the presence <strong>of</strong> excessive losses, e.g. <strong>of</strong><br />

water <strong>and</strong> salt through increased sweating <strong>and</strong> insensible loss in hot<br />

climates. They may also need to be modified in the presence <strong>of</strong> disease,<br />

e.g. gastroenteritis, which causes abnormal losses <strong>of</strong> fluid <strong>and</strong><br />

electrolyte from the GI tract (Fig. 3 <strong>and</strong> Table 3).<br />

Table 1: Approximate daily water balance in health<br />

Intake (ml)<br />

Output (ml)<br />

Water from beverages 1200 Urine 1500<br />

Water from solid food 1000<br />

Insensible losses from skin<br />

<strong>and</strong> lungs<br />

900<br />

Metabolic water from oxidation 300 Faeces 100<br />

13

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