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Intensity-modulated radiotherapy by means of static tomotherapy: A ...

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832 M. Oldham and S. Webb: <strong>Intensity</strong>-<strong>modulated</strong> <strong>radiotherapy</strong> 832<br />

FIG. 7. Comparison <strong>of</strong> predicted dotted lines with measured solid lines<br />

absolute isodose lines cGy for the single intensity <strong>modulated</strong> field irradiation.<br />

The predicted dose distribution corresponding to the nine<br />

intensity-<strong>modulated</strong> fields as found <strong>by</strong> the forward dose calculation<br />

step outlined in Sec. II A is shown in Fig. 8a.<br />

Isodoses, interpolated from dose points on a2mmgrid spacing,<br />

are shown after the distribution has been normalized to<br />

the maximum dose in the plane. As the distribution was only<br />

computed for the region inside the circular outer OAR <strong>of</strong><br />

Fig. 2, the very low isodoses follow this OAR at the edges.<br />

In reality the isodoses will not assume this circularity at the<br />

edge. At delivery, Fig. 5 shows that a total <strong>of</strong> almost 200<br />

monitor units were delivered to the perspex phantom via the<br />

62 component vane configurations. This arrangement led to a<br />

maximum dose in the PTV as predicted <strong>by</strong> the planning s<strong>of</strong>tware<br />

<strong>of</strong> 0.82 Gy Appendix B. On completion <strong>of</strong> the delivery,<br />

the film was developed and the delivered dose distribution<br />

was scanned Fig. 8b via an optical densitometer<br />

Wellhöffer WP102. The scan performed was a 2D net scan<br />

with each line <strong>of</strong> the scan containing 16 values per mm along<br />

its length, and with line spacing <strong>of</strong> 0.5 cm. The 2D netscan<br />

lines were performed in both the x and y directions. Conversion<br />

from optical density values to dose values was achieved<br />

using a calibration curve obtained from irradiations <strong>of</strong> other<br />

verification films in the same pack.<br />

The predicted and measured dose distributions Figs. 8a<br />

and 8b were compared <strong>by</strong> photocopying the predicted distribution<br />

onto an OHP transparency so that it could be overlaid<br />

on top <strong>of</strong> the measured distribution. The general agreement<br />

between the two dose distributions is very good. The<br />

90% isodose line <strong>of</strong> the delivered distribution clearly shows<br />

two concavities where the OARs are adjacent to the PTV.<br />

FIG. 8. Isodoses <strong>of</strong> the computer-calculated and film-measured dose distributions.<br />

Isodose lines on both plots are starting from outter lines and moving<br />

inwards 30%, 40%, 50%, 60%, 70%, 75%, 80%, 85%, 90%, 95%,<br />

100% <strong>of</strong> the maximum dose. A scale-drawing <strong>of</strong> the PTV and OAR’s has<br />

been superimposed onto the isodose lines. a The predicted dose distribution<br />

as found <strong>by</strong> the forward dose calculation which takes into account the<br />

penumbral characteristics <strong>of</strong> the delivery technique. b The delivered dose<br />

distribution as measured <strong>by</strong> verification film.<br />

Lower isodose lines also clearly show that the dose in the<br />

OARs has been kept relatively very low compared to the<br />

dose in the PTV. All the main features <strong>of</strong> the predicted dose<br />

distribution are seen in the delivered except for the artificial<br />

circularity <strong>of</strong> low-dose isodoses at the edges. The 90% isodoses<br />

are consistently in spatial agreement to within 3 mm<br />

except for in the lower right hand region where the predicted<br />

isodose makes a small kink into the body <strong>of</strong> the PTV. At the<br />

50% isodose level consistent spatial agreement is again<br />

found to within 3 mm, the largest deviation being about 5<br />

mm. Although the general shape <strong>of</strong> the distributions agree<br />

well, the delivered distribution is asymmetrically hotter on<br />

Medical Physics, Vol. 24, No. 6, June 1997

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