Statin/Ezetimbe Combination Therapy: Emerging Evidence
Statin/Ezetimbe Combination Therapy: Emerging Evidence
Statin/Ezetimbe Combination Therapy: Emerging Evidence
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CAI<br />
THE INHIBITION OF CHOLESTEROL ABSORPTION<br />
RESULTS IN INCREASED CHOLESTEROL BIOSYNTHESIS<br />
HEPATIC<br />
BIOSYNTHESIS<br />
INTESTINAL<br />
ABSORPTION<br />
Inhibition of cholesterol<br />
absorption<br />
(ezetimibe)<br />
Food<br />
absorption<br />
synthesis<br />
30-50% absorption<br />
Cholesterol<br />
excreted in the<br />
faeces<br />
LDL-C<br />
20%<br />
CAI = cholesterol absorption inhibitor<br />
Assmann G, et al. J Am Coll Cardiol 2004;43(5, Suppl. 2):A445-A446; Goldberg AC, et al. Mayo Clin Proc. 2004 May;79(5):620-9.
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