Statin/Ezetimbe Combination Therapy: Emerging Evidence

Overall Conclusion
• A beneficial approach by selectively blocking cholesterol absorption, provides
Dual Inhibition of the two sources of cholesterol
• Statin/ Ezetimibe combination is a unique tool in the management of
dyslipidemia that offers the advantage of intensive lowering and the safety of
low dose statin monotherapy.
• Therefore Statin/ Ezetimibe combination is recommended for;
Dyslipidemic patients uncontrolled on regular dose of statin monotherapy
Dyslipidemic patients very high risk patients for whom goal of 70 mg/dl is
recommended
Dyslipidemic patients with high baseline LDL-C (need more than 50% LDL-
C reduction)