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Curriculum Vitae - Surgical Planning Laboratory

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PART I: General Information<br />

<strong>Curriculum</strong> <strong>Vitae</strong><br />

Ehud Jeruham Schmidt<br />

DATE PREPARED: September 24, 2008<br />

Name: Ehud Jeruham Schmidt<br />

Office Address: Room LM-010c, 221 Longwood Ave, Boston, MA 02115<br />

Home Address: 40 Solon Street, Newton, MA 02461<br />

E-Mail: eschmidt3@partners.org FAX: 617-278-0610<br />

Place of Birth: Haifa, Israel<br />

Education:<br />

Year Degree Institution<br />

1987 Ph. D. Applied Physics/Geophysics Stanford University,<br />

Stanford, CA<br />

1982<br />

B.A. Physics<br />

Technion<br />

, Israel Institute of<br />

Technology, Haifa, Israel<br />

Postdoctoral Training:<br />

Year Title Specialty/Discipline Place of Training<br />

1987-1990 Lady Davis Post-<br />

Doctoral Fellowship<br />

Solid State/Physics Technion, Israel Institute of<br />

Technology, Haifa, Israel<br />

Academic Appointments:<br />

Year Academic Title Institution<br />

2008-Present Lecturer<br />

Harvard Medical School,<br />

Boston, MA<br />

2001<br />

Visitin<br />

-2007 g Scientist, Cardiology<br />

Massachusetts General<br />

Hospital, Boston, MA<br />

Ehud Schmidt CV<br />

1


Hospital or Affiliated Institution Appointments:<br />

Year Title<br />

2008-Present Director, Engineering Physics, AMIGO,<br />

Radiology<br />

2001<br />

-2007 Scientist, Cardiology<br />

Hospital/Affiliated<br />

Institution<br />

Brigham and Women’s<br />

Hospital, Boston, MA<br />

Massachusetts General<br />

Hospital, Boston, MA<br />

Major Administrative Responsibilities:<br />

Year Title<br />

2008<br />

-2008<br />

-2005<br />

-2001<br />

-2000<br />

1998-2000<br />

8<br />

Director, Engineering Physics, AMIGO,<br />

Radiology<br />

2005<br />

Manager, Applied Science Lab Cardiac &<br />

Neurological MRI<br />

2001<br />

Senior Scientist, Applied Science Lab<br />

1999<br />

onal MRI Segment Manager<br />

1998<br />

a Twinspeed Product Manager<br />

Israel Marketing Manager<br />

199<br />

Senior Product Manager<br />

Interventi<br />

Sign<br />

MRI<br />

MRI<br />

Institution (local,<br />

government, foundation)<br />

Brigham and Women’s<br />

Hospital, Boston, MA<br />

General Electric<br />

Healthcare, Waukesha, WI<br />

General Electric Medical<br />

Systems, Waukesha, WI<br />

General Electric Medical<br />

Systems, Waukesha, WI<br />

General Electric Medical<br />

Systems, Waukesha, WI<br />

General Electric Medical<br />

Systems, Waukesha, WI<br />

Elscint Ltd., Haifa, Israel<br />

1991-1997<br />

MRI Product Manager<br />

Elscint Ltd., Haifa, Israel<br />

1990-1991<br />

1987-1988<br />

Senior Physicist<br />

ntist<br />

Scie<br />

Franztech Ltd., Haifa,<br />

Israel<br />

Mobil Research &<br />

Development, Dallas, TX<br />

Professional Societies:<br />

2<br />

Ehud Schmidt CV


Year Society Role<br />

1991-Present ISMRM<br />

Member<br />

2005-Present<br />

1982-2002<br />

American Heart Association<br />

American Physical Society<br />

Member<br />

Member<br />

Awards and Honors:<br />

Year<br />

1998-2000<br />

1987<br />

1982<br />

Name of Award<br />

Lady Davis Post-Doctoral Fellowship<br />

PhD Cum Laude, Stanford University<br />

BA with Honors, Technion<br />

Part II: Research, Teaching, and Clinical Contributions<br />

A. Narrative report (500 words or less) of Research, Teaching, and Clinical Contributions.<br />

Please focus primarily on the areas in which most of your time and effort is spent.<br />

Clinical Contributions-<br />

As a scientist in the GE Applied Science Lab (ASL) (2001-2008), my emphasis was on clinical<br />

application of improved spatial and temporal resolution cardiac MRI techniques, in order to<br />

visualize heart-chamber geometry, and visualize ablation lesions after Electro-Physiology ablation<br />

procedures. As a result of these techniques, the number of cardiac MRI procedures at several<br />

institutions (Mayo Clinic, MGH) increased by more than 300%. In addition, the 1 st tools to port<br />

pre-operative MRI images into the EP operating room and register them to the operating-room<br />

frame of reference, for use intra-operatively, were developed.<br />

In support of emergency radiology at Massachusetts General Hospital (2001-2008), new<br />

techniques were developed to allow for rapid assessment (


later applied to the construct of small (


MRI-Guided<br />

Electrophysiology<br />

Removing Magneto-Hydrodynamic<br />

effects from ECG<br />

Co-PI (w/ Laurence Epstein-BWH cardiology)<br />

Co-PI (w/Roger Mark-MIT HST)<br />

D. Report of Teaching<br />

Regional, national, or international contributions<br />

Invited Presentations<br />

2008<br />

Interventional MRI Symposium<br />

Sunnybrook Health Science Center, Toronto, ON<br />

E. Report of Clinical Activities<br />

1. Description of clinical practice<br />

Supported the departments of Radiology and Cardiology in the use of MRI for the diagnosis and<br />

treatment of cardiac, neurological and prostate pathologies. Sites of practice are major academic<br />

teaching hospitals (MGH, Brigham and Women’s).<br />

2. Patient load<br />

Focus is on use of MRI for the improved diagnosis of complex cases, including use of MRI for<br />

tertiary and emergency care.<br />

3. Clinical contributions<br />

-Use of Cardiac MRI to detect Post-RF ablation necrosis (MGH)<br />

-Use of Cardiac MRI to provide geometry of cardiac chambers (MGH/Brigham and Women’s)<br />

-Use of Cardiac MRI in the Emergency room to detect acute infarction (MGH)<br />

- Application of Arterial Spin Labeling for non-contrast detection of perfusion in acute stroke<br />

(MGH)<br />

-Application of diffusion MRI for improved tumor specificity (BWH)<br />

Ehud Schmidt CV<br />

5


-Application of motion-compensation for improved brain imaging of uncooperative, nonanesthetized<br />

patients (Univ. California San Diego)<br />

Part III: Bibliography<br />

Original Articles<br />

1. Schmidt EJ, Velasco K, and Nur A, Quantifying Solid-Fluid Interfacial Phenomena in<br />

Porous Rocks with Proton Nuclear magnetic Resonance. J. Appl. Phys. 1986; 59 (8): 2788.<br />

2. Schmidt EJ, and Nur A, Wideband Acoustic Response of Fluid Saturated Porous Rocks. J.<br />

Acoust. Soc. Am. 1986; 79 (51), S62.<br />

3. Wang Z, Schmidt EJ and Auld B, Acoustic Wave Transmission through One- Dimensional<br />

PZT-Epoxy composites., Ultrasonics Symposium 1986, and Ultrasonics 1988; August.<br />

4. Schmidt EJ, “ Reply to ‘ Comment on Quantifying Solid-Fluid interfacial Phenomena in<br />

Porous Rocks with Proton Nuclear Magnetic Resonance’”, J. Appl. Phys. 1988; 63 (4):<br />

1245.<br />

5. Schmidt EJ, The Wideband Acoustic Response of Fluid Saturated Porous Rocks: Theory<br />

and Preliminary Results Using Waveguided Samples. J. Acoust. Soc. Am. 1988; 83 (6):<br />

2027.<br />

6. Givens W and Schmidt EJ, The CRIMM Model For Multiphase Capillary Pressure in<br />

Porous media. Soc. Prof. Well Log Analy. 1988; July.<br />

7. Schuster I, Polturak E, Swirsky Y, Schmidt EJ, and Lipson S, Vacancy Induced Atomic<br />

Motion in 3 He- 4 He Mixture Crystals on the melting Curve studied by NMR Imaging. Jour.<br />

Low Temp. Phys. 1996; 104 (4).<br />

8. Reddy VY, Malchano ZJ, Holmvang G, Schmidt EJ, D'Avila A, Houghtaling C, Chan RC,<br />

Ruskin JN, Integration of cardiac magnetic resonance imaging with three-dimensional<br />

electroanatomic mapping to guide left ventricular catheter manipulation feasibility in a<br />

porcine model of healed myocardial infarction. J. Am. Coll. Cardiol. 2004; (44), 11: 2202.<br />

9. Malchano Z., Neuzil P, Cury RC, Holmvang G, Weichet JI, Schmidt EJ, Ruskin<br />

JN ,Reddy VY, Integration of Cardiac CT/MR Imaging with Three-Dimensional<br />

Electroanatomical Mapping to Guide Catheter Manipulation in the Left Atrium:<br />

Implications for Catheter Ablation of Atrial Fibrillation. Journal of Cardiovascular<br />

Electrophysiology 2006;17 (11): 1221<br />

Ehud Schmidt CV<br />

6


10.Heist D, Arzola-Castaner D, Malchano Z, Holmvang G, Basu-Ray I, Pomerantseva I,<br />

Schmidt EJ, Houghtaling C, McPherson C, Singh J, Injection of bone marrow-derived<br />

Cells into a porcine myocardial Infarction model guided by integration of<br />

Electroanatomical mapping and Magnetic Resonance Imaging. Heart Rhythm 2005; 2,<br />

(5), S109<br />

11.Schmidt EJ, Reddy VY, and Ruskin JN, Nonenhanced magnetic resonance imaging for<br />

characterization of acute and subacute radiofrequency ablation lesions., Heart Rhythm<br />

2007;4 (2): 215<br />

12.Schmidt EJ, Yoneyama R, Dumoulin CL, Darrow RD, Klein E, and Hayase M, Detailed<br />

3D Coronary Motion Tracking in swine Models using MR Tracking catheters. in<br />

print ,JMRI 2008<br />

13.Dukkipati SR, Mallozi RP, Schmidt EJ, D’Avila A, Holmvang G, Guhde R, Darrow RD,<br />

Slavin G, Fung M, Malchano Z, Kampa G, Dando JD, McPherson C, Foo TK, Ruskin JN,<br />

Dumoulin CL, Reddy VY, Electroanatomic mapping of the left ventricle in a Porcine<br />

model of chronic myocardial infarction using Magnetic Resonance-Tracking. Circulation<br />

118;853-862 2008<br />

14.Reddy VY, Schmidt EJ, Holmvang G, and Fung M, Arrhythmia recurrence after atrial<br />

fibrillation ablation: Can Magnetic resonance imaging identify gaps in atrial ablation<br />

lines?, J. Cardiovascular Electrophysiology, 19, 4, 434-437, 2007<br />

15.Cury RC, Shash K, Nagurney JT, Rosito G, Shapiro MD, Nomura CH, Abbara S,<br />

Bamberg F, Ferencik M, Schmidt EJ, Brown DF, Hoffmann U, Brady TJ Cardiac Magnetic<br />

Resonance With T2-Weighted Imaging Improves Detection of Patients With Acute<br />

Coronary Syndrome in the Emergency Department, Circulation 118; 837-844 2008<br />

Proceedings of Meetings<br />

1. Schmidt EJ , Dumoulin CL, Hayase M , Reddy VY , Holmvang G , and Brady T, An Intra-<br />

Vascular Imaging Catheter Including Imaging, Tracking and Centering Components,.<br />

Eleventh meeting of the International Society of Magnetic Resonance in Medicine 2003;<br />

Toronto, Canada.<br />

2. Schmidt EJ, Yoneyama R, Dumoulin CL, Hayase M, and Klein E, Coronary Artery Motion<br />

Tracking in Swine using MR Tracking Catheters. 2004 meeting of the Society for<br />

Cardiovascular Magnetic Resonance 2004; Barcelona, Spain.<br />

Ehud Schmidt CV<br />

7


3. Schmidt EJ, Reddy VY, Hayase M, Basu Ray I, and Dumoulin CL, Self-Expandable Intra-<br />

Vascular MR Imaging and MR tracking Catheters. Thirteenth meeting of the International<br />

Society of Magnetic Resonance in Medicine, 2005; Miama, FL.<br />

4. Mallozzi RP, Darrow RD, Guhde R, Ludke S, Kampa G, Schmidt EJ, Cline HE, Reddy<br />

VY, and Dumoulin CL, MR Guided Electrophysiology Using Active MR Tracking.<br />

Thirteenth meeting of the International Society of Magnetic Resonance in Medicine 2005,<br />

Miami, Florida.<br />

5. Kiruluta A, Qasmieh IF, Schmidt EJ , Yoneyama R , and Dumoulin CL, Motion<br />

Correction in High-Resolution Coronary MRI Using Measurements from in-situ Tracking<br />

and Imaging Catheters. Thirteenth meeting of the International Society of Magnetic<br />

Resonance in Medicine 2005; Miami, Florida.<br />

6. Mallozzi RP, Guhde RA , Darrow RD, Fiveland E, Ludke S , Kampa G, Dando JD, Just D,<br />

Nee E, Schmidt EJ, Cline HE , Holmvang G, Malchano Z , Reddy VY, and Dumoulin CL ,<br />

MR Guided Electrophysiology. 17 th meeting of the MR Angio Club 2005; Beijing, China.<br />

7. Schmidt EJ , Holmvang G , Guhde R , Darrow RD , Slavin G , Fung M , Mallozzi RP,<br />

Dumoulin CL, Kampa G, Dando JD , Foo TK , Malchano Z , Reddy VY, MRI-Guided<br />

Navigation for Electrophysiological Interventions using MRI-Tracked Catheters Overlaid<br />

on Pre-Acquired images. Ninth annual meeting of the Society of Cardiovascular Magnetic<br />

Resonance 2006; Miami, Florida.<br />

8. Dukkipati SR, Schmidt EJ, Holmvang G, Gudhe R, Darrow R, Slavin G, Fung M, Mallozi<br />

RP, Dumoulin CL, Malchano Z, Kampa G, Dando J, Mcpherson C, Foo TK, Ruskin JN,<br />

and Reddy VY, Electroanatomic Substrate Mapping of the Left Ventricle Using Real-<br />

Time iMRI. Ninth annual meeting of the Society of Cardiovascular Magnetic Resonance<br />

2006; Miami, Florida.<br />

9. Mallozzi RP, Guhde RA, Fiveland E, Darrow RD, Dumoulin CL, Schmidt EJ, Dando JD,<br />

Just DE , Holmvang G, Malchano ZJ, Dukkipati SR, and Reddy VY, MR-guided<br />

Electrophysiology Interventions. Fourteenth meeting of the International Society of<br />

Magnetic Resonance in Medicine 2006; Seattle, Washington.<br />

10.Schmidt EJ, D'Avila A, Holmvang G, Thiagalingam A, Guhde R, Darrow R, Mallozzi RP,<br />

Dumoulin CL, Dando JD, Malchano Z, and Reddy VY, MRI-Guided Mapping and<br />

Pulmonary-Vein Ablation in Swine Models using MRI-Tracking. 10 th annual meeting of<br />

the Society for Cardiovascular Magnetic Resonance 2007, Rome, Italy.<br />

Ehud Schmidt CV<br />

8


11.Thiagalingam A, Schmidt E, D'Avila A, Holmvang G, Darrow R, Mallozzi RP, Dumoulin<br />

CL, Dando JD, and Reddy VY, Feasibility of MRI-Guided Mapping and Pulmonary Vein<br />

Ablation in a Swine Model. 2007 Heart Rhythm Society Meeting 2007; Denver, Colorado.<br />

12.Fung MM, Schmidt EJ, Holmvang G, Hood MN, and VB Ho, Novel approach for ECG<br />

Gated Dynamic Contrast Enhanced MRA. meeting of the MR Angio Club 2007; Istanbul,<br />

Turkey .<br />

13.Fung MM, Schmidt EJ, Holmvang G, Hood MN, and VB Ho, Robust Coronary Artery<br />

Imaging using multiphase-multislab free breathing 3d SSFP. meeting of the MR Angio<br />

Club 2007; Istanbul, Turkey .<br />

14.Fung MM, Wei JL, Grant A, Shankaranarayanan A, Madhuranthakam A, Carillo A,<br />

Schmidt EJ, and Rovsky N, Accelerated whole-chest ECG-gated 3d contrast enhanced<br />

pulmonary angiography with integrated calibration. meeting of the MR Angio Club 2007;<br />

Istanbul, Turkey.<br />

15.Shankaranarayanan A, Roddey C, White N, Han ET, Rettmann D, Santos J, Schmidt EJ,<br />

and Dale A, Motion insensitive 3D imaging using a novel real-time image-based<br />

prospective motion correction method (3D PROMO). Fifteenth meeting of the<br />

International Society of Magnetic Resonance in Medicine 2007; Berlin, Germany.<br />

Reviews, Chapters, and Editorials<br />

1. Schmidt EJ, Velasco K, and Nur A, Quantifying Solid-Fluid Interfacial Phenomena in<br />

Porous Rocks with Proton NMR. Proceedings of Symposium on the Chemistry and Physics<br />

of Composite Media (edited by Tomkiewitz M and Sen PN, Electrochemical Society Press,<br />

Pennington, New Jersey) 1985; Vol. 85-8.<br />

Thesis<br />

1. Schmidt EJ. Wideband Acoustic Response of Flud Staruated Rocks [dissertation]. Stanford<br />

(CA): Stanford Univer.; 1987.<br />

Patents<br />

1. Schmidt EJ inventor; General Electric Corporation assignee. Expandable Multi-channel<br />

Radio-Frequency Receiver Coil for High-Resolution Intra-Cardiac Magnetic Resonance<br />

Imaging, GEMS8081.204 2004 (under review).<br />

2. Fung MM, Schmidt EJ, Holmvang, G, Ho VG inventors; General Electric Corporation,<br />

Massachusetts General Hospital, National Naval Medical University assignees. Method<br />

Ehud Schmidt CV<br />

9


and apparatus for contrast inflow dynamic MR Angiography, US docket GEMS 8081.410.<br />

2008 Jan (under review)<br />

Ehud Schmidt CV<br />

10

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