advances-in-protein-chemistry

Figure 16: Various Features at the Protherm Site.
Figure 17: Various features of Protherm Version 3.0. Figure 18: List of Important Information for Protein Folding Experiment at Protein Folding
Database (Pfd).
Protein Folding Database (Pfd)
It is really an informative, easily accessible and innovative resource and database that facilitates protein folding data of more than
50 different proteins belongs to various families. Data of structural, kinetic as well as thermodynamic in nature is available on protein
folding database that could be accessed through web platform. With the various useful features it links with the other protein databases
as well [27].
Protein Folding Database 2.0 provides freely accessible and centralized data repository. It has been built as a comparative repository
providing kinetic and thermodynamic features for the folding of protein in a useful and user friendly way [27].
Site Directed Mutator (Sdm)
SDM is a server for predicting effects of mutations on protein stability and malfunction. Site Directed Mutator is a statistical potential
energy function that exercises environment-specific amino-acid replacement frequencies within homologous protein families to compute
a stability score, which is corresponding to the free energy difference between the wild-type and mutant protein [28].
SRide
SRide server provides data that could be employed for the calculation of van der Waals atomic radius among the amino acids. The
residues present in the polypeptide and play a crucial role for the stability of protein molecules are called stabilizing residues (SRs).
These residues are selected by using various methods like interaction of a given residue with its neighboring residues and observing the
evolutionary conservation in the protein structures [29].
OMICS Group eBooks
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