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Manitoba and the Emerging Bioeconomy

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Example: Betulin<br />

Has been shown to help wounds heal faster <strong>and</strong> cut inflammation.<br />

Many cosmetic companies, touting it as a skin toner <strong>and</strong> restorer, add<br />

birch bark extract to various products.<br />

Betulin can be easily converted to betulinic acid, which possesses a wide<br />

spectrum of biological <strong>and</strong> pharmacological activities.<br />

antimalarial <strong>and</strong> anti-inflammatory activities<br />

anti-HIV activity <strong>and</strong> cytotoxicity against a variety of tumor cell lines<br />

comparable to some clinically used drugs.<br />

Betulinic acid is specifically cytotoxic to several tumor cell lines<br />

(melanoma) by inducing apoptosis in cells.<br />

Fields of application:<br />

1. Raw material for pharmaceutical production;<br />

2. As a main active ingredient in parfumery-cosmetic products;<br />

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