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mEdiCal<br />

Scientific & Biomedical microSyStemS llc, columBia, md<br />

Laser Vision Patient Unit/<br />

Data Receiver<br />

Wireless Data Transfer<br />

Flash Memory<br />

Storage (SD)<br />

Secure Permament<br />

Patient Record<br />

Patient Product<br />

Capsule System<br />

Patient test<br />

Capsule Endoscope<br />

External Communication<br />

Sensors (disposable)<br />

Figure 2. The new endoscopy system incorporates a smaller, more energy-efficient imaging pill with<br />

scanning imager; a portable data controller with sensors that stick to the abdomen and resemble EKG<br />

pads and leads; and software <strong>for</strong> data analysis.<br />

“since each fabrication<br />

run of these devices takes<br />

many weeks and thousands<br />

of dollars, the modeling<br />

we’ve been able to do has<br />

been critical in keeping this<br />

project moving <strong>for</strong>ward<br />

aggressively and on budget.”<br />

but RF’s power demands severely limit<br />

the power available <strong>for</strong> use by miniaturized<br />

devices. They also reduce battery life<br />

and require larger pills than might otherwise<br />

be possible. Energy inefficiency is a<br />

major reason why current imaging pills<br />

feature a resolution of only about 70 kilopixels,<br />

running at two frames/second. The<br />

resulting images are often disjointed and<br />

herky-jerky, especially when the capsule is<br />

being propelled quickly as happens during<br />

a bout of peristalsis.<br />

By contrast, SB Microsystems is helping<br />

Innurvation develop a data channel with a<br />

1 Mb/sec data transmission rate and a longer-life<br />

imaging pill with a 360° radial scanning<br />

imager that together will enable much<br />

sharper, continuous imagery (Figure 3).<br />

The communications channel has been<br />

tested successfully in pigs and is moving to<br />

human trials this year, while the scanning<br />

imager is a later phase of the project.<br />

“The human body is basically a big bag<br />

of salt water and there are many situations<br />

and sets of conditions where transmitting<br />

data via acoustic waves through<br />

this medium is very energy-efficient,”<br />

said Jamieson. “Traditional endoscopes<br />

with a high-resolution CMOS imager at<br />

their tip produce really sharp images.<br />

The goal here is to achieve high-resolution<br />

endoscope-type clarity and coverage<br />

in a imaging pill.”<br />

In the system under development, the<br />

acoustic wave source is a piezoelectric<br />

(PZT) element. SB Microsystems is using<br />

COMSOL’s piezo-acoustic tools <strong>for</strong><br />

multiple aspects of this project, from optimizing<br />

the behavior of the PZT acoustic<br />

source, to exploring acoustic interactions<br />

with different tissues, to implementing<br />

multiple receiver network designs in order<br />

to minimize multipath interference<br />

(Figure 4).<br />

“These issues have required us to<br />

develop an understanding of the coupling<br />

between the acoustic, electric and<br />

mechanical domains, and the integrated,<br />

expert physics capabilities of COMSOL<br />

Multiphysics have been absolutely critical<br />

to the success of that ef<strong>for</strong>t,” said Jamieson.<br />

“For example, by coupling the<br />

piezoelectric and pressure acoustics user<br />

interfaces we were able to optimize PZT<br />

material choice and sensor geometry to<br />

design a transmitter that is very nearly<br />

omnidirectional, a critical requirement.”<br />

Coupling the pressure acoustics and<br />

mechanical domains, meanwhile, enabled<br />

the design team to analyze the<br />

interactions of acoustic signals with different<br />

tissues, which provided the ability<br />

to understand and to accommodate important<br />

issues such as multipath interference<br />

and signal fade.<br />

Variable Rate Sidewall Scanning<br />

Innurvation Solution<br />

1 2 3<br />

1 2<br />

Figure 3. 360° radial scanning technology produces much sharper and continuous imagery.<br />

1<br />

2<br />

3<br />

3<br />

3 0 // C o m s o l N E W s 2 0 1 1<br />

➮<br />

Cov ToC + – A<br />

➭<br />

29-31 CN SBMicrosystems 2011.indd 30 5/13/11 10:12 AM

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