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USciences Bulletin - University of the Sciences in Philadelphia

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THE BULLETIN: SCHOLARLY ACTIVITY PAGE 31<br />

KARIN GRÄVARE<br />

SILBERNAGEL✦, R. Willy+,<br />

I. Davis+, “Pre- and Post-Injury<br />

Runn<strong>in</strong>g Mechanics <strong>in</strong> a Patient<br />

with an Achilles Tendon Rupture”<br />

at <strong>the</strong> American Physical<br />

Therapy Association Comb<strong>in</strong>ed<br />

Sections Meet<strong>in</strong>g, Chicago,<br />

February 8–11, 2012.<br />

JOAN F. WARD✦ served as<br />

a workshop facilitator and<br />

presenter at <strong>the</strong> Physician<br />

Assistant Education Association<br />

Faculty Development Institute<br />

Cl<strong>in</strong>ical Coord<strong>in</strong>ators Workshop:<br />

Survival 101, Alexandria, Virg<strong>in</strong>ia,<br />

March 23–24, 2012.<br />

Pr<strong>of</strong>essional Activity<br />

THERESE E. JOHNSTON✦<br />

• served as a grant reviewer for<br />

<strong>the</strong> Department <strong>of</strong> Defense<br />

Congressionally Directed<br />

Medical Research Programs<br />

(CDMRP) Sp<strong>in</strong>al Cord Injury<br />

Cl<strong>in</strong>ical Trial and Sp<strong>in</strong>al Cord<br />

Injury Qualitative Research<br />

Panels, January 18–20, 2012.<br />

• served as a grant reviewer for<br />

<strong>the</strong> Veterans Adm<strong>in</strong>istration<br />

Rehabilitation Research Merit<br />

Award, February 5–7, 2012.<br />

• served as a grant reviewer for<br />

<strong>the</strong> Craig H. Neilsen Foundation,<br />

Sp<strong>in</strong>al Cord Injury Rehabilitation<br />

Grants, March 1–10, 2012.<br />

KARIN RICHARDS✦ was<br />

named to serve on <strong>the</strong> National<br />

Wellness Institute Council on<br />

Wellness Accreditation and<br />

Education (CWAE).<br />

Publications<br />

M. E. O’Neil+, M. Fragala-<br />

P<strong>in</strong>kham+, ROGER I.<br />

IDEISHI✦, SIOBHAN K.<br />

IDEISHI✦, “Community-Based<br />

Programs for Children and Youth:<br />

Our Experiences <strong>in</strong> Design,<br />

Implementation, and Evaluation,”<br />

Physical & Occupational Therapy <strong>in</strong><br />

Pediatrics, 32(2):111–119, 2012.<br />

THERESE E. JOHNSTON✦,<br />

C. M. Modlesky+, R. R. Betz+,<br />

R. T. Lauer+, “Muscle Changes<br />

Follow<strong>in</strong>g Cycl<strong>in</strong>g and/or<br />

Electrical Stimulation <strong>in</strong> Pediatric<br />

Sp<strong>in</strong>al Cord Injury,” Archives <strong>of</strong><br />

Physical Medic<strong>in</strong>e and Rehabilitation<br />

92(12):1937–1943, 2011.<br />

KARIN GRÄVARE<br />

SILBERNAGEL✦, R. Willy+,<br />

I. Davis+, “Pre- and Post-Injury<br />

Runn<strong>in</strong>g Analysis along with<br />

Measurements <strong>of</strong> Strength and<br />

Tendon Length <strong>in</strong> a Patient with<br />

a Surgically Repaired Achilles<br />

Tendon Rupture,” Journal <strong>of</strong> Orthopaedic<br />

& Sports Physical Therapy,<br />

doi:10.2519/jospt.2012.3913,<br />

January 25, 2012.<br />

H. Alfredson+, J. Cook+, KARIN<br />

GRÄVARE SILBERNAGEL✦,<br />

J. Karlsson+, “Pa<strong>in</strong> <strong>in</strong> <strong>the</strong> Achilles<br />

Region,” chapter 37 <strong>in</strong> Brukner<br />

& Khan’s Cl<strong>in</strong>ical Sports Medic<strong>in</strong>e,<br />

4th ed., P. Brukner, K. Khan, eds.,<br />

McGraw-Hill, pp. 776–805, 2012.<br />

K. Manal+, KARIN GRÄVARE<br />

SILBERNAGEL✦, T. S. Buchanan+,<br />

“A Real-Time EMG-Driven<br />

Musculoskeletal Model <strong>of</strong> <strong>the</strong><br />

Ankle,” Multibody System<br />

Dynamics, November 23, 2011<br />

(E-pub ahead <strong>of</strong> pr<strong>in</strong>t).<br />

Cont<strong>in</strong>ued from page 29<br />

and her colleague Michael Pack, MD, also a gastroenterologist<br />

at <strong>the</strong> Perelman School <strong>of</strong> Medic<strong>in</strong>e, began<br />

study<strong>in</strong>g biliary atresia as members <strong>of</strong> <strong>the</strong> Fred and<br />

Suzanne Biesecker Center for Pediatric Liver Disease, at<br />

The Children’s Hospital <strong>of</strong> <strong>Philadelphia</strong>. To her<br />

surprise, Dr. Wells learned that <strong>the</strong>re had been a third<br />

biliary atresia epidemic <strong>in</strong> <strong>the</strong> Australian lambs <strong>in</strong> 2007.<br />

She was able to contact <strong>the</strong> Australian veter<strong>in</strong>arian<br />

<strong>in</strong>volved, Dr. Steve Whittaker, and learned that<br />

pigweed was believed to be <strong>the</strong> most likely culprit.<br />

S<strong>in</strong>ce it would not be feasible to grow <strong>the</strong> plant <strong>in</strong> <strong>the</strong><br />

United States, <strong>the</strong> U.S. group collaborated with Dr.<br />

Whittaker to provide a quantity <strong>of</strong> <strong>the</strong> plant for study.<br />

Dr. Porter and Dr. Kyung A. Koo, a postdoctoral<br />

researcher on <strong>the</strong> project, fractionated <strong>the</strong> plant <strong>in</strong>to<br />

multiple components, and Dr. Pack’s group identified<br />

<strong>the</strong> toxic fractions us<strong>in</strong>g a novel assay his lab devised<br />

to monitor bile flow and bile duct morphology <strong>in</strong><br />

larval zebrafish. Dr. Pack’s group uses <strong>the</strong> zebrafish to<br />

study <strong>the</strong> pathogenesis <strong>of</strong> heritable bile duct disorders;<br />

thus he was uniquely prepared to collaborate on <strong>the</strong><br />

pigweed project. Dr. Porter and his research team<br />

are now work<strong>in</strong>g to determ<strong>in</strong>e <strong>the</strong> structure <strong>of</strong> <strong>the</strong><br />

compounds responsible for <strong>the</strong> toxicity.<br />

“Understand<strong>in</strong>g <strong>the</strong> cause <strong>of</strong> <strong>the</strong> disease <strong>in</strong> humans<br />

is an ultimate goal,” said Dr. Porter.<br />

Once <strong>the</strong> structures are identified, he will be able to<br />

work with Dr. Wells and Dr. Pack to study <strong>the</strong> new<br />

zebrafish model <strong>of</strong> biliary atresia and develop o<strong>the</strong>r<br />

animal models <strong>of</strong> <strong>the</strong> disease.<br />

“It’s not <strong>the</strong> highest <strong>in</strong>cidence disease <strong>in</strong> <strong>the</strong> world,<br />

but it is one that is pretty devastat<strong>in</strong>g,” said Dr.<br />

Porter. Biliary atresia is <strong>the</strong> major reason for liver<br />

transplants <strong>in</strong> <strong>the</strong> pediatric population.

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