2010 Annual Report - Institute for Molecular Bioscience - University ...

imb annual report 2010
106
Leong, G.M., Kee, A.J., Millard, S.M.,
Martel, N., Eriksson, N., Turner, N.,
Cooney, G.J., Hardeman, E.C., and
Muscat, G.E.O. (2010). The Ski protooncogene
regulates body composition
and suppresses lipogenesis. International
Journal of Obesity 34: 524-536.
Little, M., Georgas, K., Pennisi, D., and
Wilkinson, L. (2010). Kidney development:
two tales of tubulogenesis. Organogenesis
in Development 90: 193-229.
Lusis, M., Li, J., Ineson, J., Christensen,
M.E., Rice, A., and Little, M.H. (2010).
Isolation of clonogenic, long-term self
renewing embryonic renal stem cells. Stem
Cell Research 5: 23-39.
MacDonald, K.P.A., Palmer, J.S., Cronau,
S., Seppanen, E.J., Olver, S., Raffelt,
N.C., Kuns, R., Pettit, A.R., Clouston, A.,
Wainwright, B.J., Branstetter, D., Smith,
J., Paxton, R.J., Cerretti, D.P., Bonham,
L., Hill, G.R., and Hume, D. (2010). An
antibody against the colony-stimulating
factor 1 receptor (CSF1R) depletes the
resident subset of monocytes and tissue
and tumor-associated macrophages but
does not inhibit inflammation. Blood 116:
3955-3963.
Markey, K.A., Burman, A.C., Banovic, T.,
Kuns, R.D., Raffelt, N.C., Rowe, V., Olver,
S.D., Don, A.L.J., Morris, E.S., Pettit, A.R.,
Wilson, Y.A., Robb, R.J., Randall, L.M.,
Korner, H., Engwerda, C.R., Clouston,
A.D., MacDonald, K.P.A., and Hill, G.R.
(2010). Soluble lymphotoxin is an important
effector molecule in GVHD and GVL. Blood
115: 122-132.
McCann, F.E., Palfreeman, A.C., Andrews,
M., Perocheau, D.P., Inglis, J.J., Schafer,
P., Feldmann, M., Williams, R.O., and
Brennan, F.M. (2010). Apremilast, a novel
PDE4 inhibitor, inhibits spontaneous
production of tumour necrosis factor-alpha
from human rheumatoid synovial cells and
ameliorates experimental arthritis. Arthritis
Research & Therapy 12: R107.
McFarlane, L., and Wilhelm, D. (2010).
Non-Coding RNAs in Mammalian Sexual
Development. Sexual Development 3:
302-316.
McMahon, S.K., Pretorius, C.J.,
Ungerer, J.P.J., Salmon, N.J., Conwell,
L.S., Pearen, M.A., and Batch, J.A.
(2010). Neonatal Complete Generalized
Glucocorticoid Resistance and Growth
Hormone Deficiency Caused by a
Novel Homozygous Mutation in Helix
12 of the Ligand Binding Domain of the
Glucocorticoid Receptor Gene (NR3C1).
HAN SHENG CHIU: ART OF SEX SCIENCE
The art is a mosaic picture containing all
of my whole-mount in situ hybridisation
results on an organ called genital
tubercle also known as external genitalia,
with a combination of 81 different
pictures of mouse genital tubercle.
Journal of Clinical Endrocrinology and
Metabolism 95: 297-302.
Ovchinnikov, D.A., DeBats, C.E.E., Sester,
D.P., Sweet, M.J., and Hume, D.A. (2010).
A conserved distal segment of the mouse
CSF-1 receptor promoter is required for
maximal expression of a reporter gene
in macrophages and osteoclasts of
transgenic mice. Journal of Leukocyte
Biology 87: 815-822.
Papathanasiou, P., Tunningley, R.,
Pattabiraman, D.R., Ye, P., Gonda, T.J.,
Whittle, B., Hamilton, A.E., Cridland, S.O.,
Lourie, R., and Perkins, A.C. (2010). A
recessive screen for genes regulating
hematopoietic stem cells. Blood 116:
5849-5858.
Pearen, M.A., and Muscat, G.E.O. (2010).
Minireview: Nuclear hormone receptor
4A signaling: Implications for metabolic
disease. Molecular Endocrinology 24:
1891-1903.
Pennisi, D.J., Chiu, H.S., Vinay, K.S.,
Wilkinson, L., Zhang, P.M., and Little,
M.H. (2010). Mice null for Crim1 display
altered BMP/TGF beta signaling, defects
in multiple organ systems and die in utero
with severe cardiovascular defects. In
69th Annual Meeting of the Society-for-
Developmental-Biology/Japanese-Societyof-Developmental-Biologists,
AUG 05-09,
2010, (480-481), Albuquerque NM.
Polanco, J.C., Wilhelm, D., Davidson, T.L.,
Knight, D., and Koopman, P. (2010). Sox10
gain-of-function causes XX sex reversal in
mice: implications for human 22q-linked
disorders of sex development. Human
Molecular Genetics 19: 506-516.
Raggatt, L.J., and Partridge, N.C. (2010).
Cellular and molecular mechanisms of
bone remodeling. Journal of Biological
Chemistry 285: 25103-25108.
Raichur, S., Fitzsimmons, R.L., Myers,
S.A., Pearen, M.A., Lau, P., Eriksson,
N., Wang, S.M., and Muscat, G.E.O.
(2010). Identification and validation of the
pathways and functions regulated by the
orphan nuclear receptor, ROR alpha1, in
skeletal muscle. Nucleic Acids Research
38: 4296-4312.
Rumballe, B., Georgas, K., Wilkinson, L.,
and Little, M. (2010). Molecular anatomy
of the kidney: What have we learned from
gene expression and functional genomics
Pediatric Nephrology 25: 1005-1016.
Sabin, M.A., Clemens, S.L., Saffery, R.,
McCallum, Z., Campbell, M.W., Kiess,
W., Crimmins, N.A., Woo, J.G., Leong,
G.M., Werther, G.A., Ukoumunne, O.C.,
and Wake, M.A. (2010). New directions
in childhood obesity research: how a
comprehensive biorepository will allow
better prediction of outcomes. BMC
Medical Research Methodology 10: 100.
Schroder, K., and Tschopp, J. (2010). The
inflammasomes. Cell 140: 821-832.
Schroder, K., Zhou, R., and Tschopp,
J. (2010). The NLRP3 inflammasome: a
sensor for metabolic danger Science 327:
269-300.
Smith, A.G., and Sturm, R.A. (2010).
Multiple genes and locus interactions
in susceptibility to vitiligo. Journal of
Investigative Dermatology 130: 643-645.
Sousa, K.M., Villaescusa, J.C., Cajanek,
L., Ondr, J.K., Castelo-Branco, G., Hofstra,
W., Bryja, V., Palmberg, C., Bergman, T.,
Wainwright, B., Lang, R.A., and Arenas,
E. (2010). Wnt2 regulates progenitor
proliferation in the developing ventral
midbrain. Journal of Biological Chemistry
285: 7246-7253.
Spiller, C.M., Wilhelm, D., and Koopman,
P. (2010). Retinoblastoma 1 protein
modulates XY germ cell entry into G(1)/G(0)
arrest during fetal development in mice.
Biology of Reproduction 82: 433-443.
Stark, M.S., Tyagi, S., Nancarrow, D.J.,
Boyle, G.M., Cook, A.L., Whiteman,
D.C., Parsons, P.G., Schmidt, C.,
Sturm, R.A., and Hayward, N.K. (2010).
Characterization of the melanoma
miRNAome by deep sequencing. PLoS
One 5: e9685-1-e9685-9.