2010 Annual Report - Institute for Molecular Bioscience - University ...

111 publications
Publications 2010
CHEMISTRY AND STRUCTURAL
BIOLOGY (CONTINUED)
Halili, M.A., Andrews, M.R., Labzin, L.I.,
Schroder, K., Matthias, G., Cao, C.,
Lovelace, E., Reid, R.C., Le, G.T., Hume,
D.A., Irvine, K.M., Matthias, P., Fairlie,
D.P., and Sweet, M.J. (2010). Differential
effects of selective HDAC inhibitors on
macrophage inflammatory responses to
the Toll-like receptor 4 agonist LPS. Journal
of Leukocyte Biology 87: 1103-1114.
Harrison, R.S., Ruiz-Gomez, G., Hill, T.A.,
Chow, S.Y., Shepherd, N.E., Lohman,
R.J., Abbenante, G., Hoang, H.N., and
Fairlie, D.P. (2010). Novel Helix-Constrained
Nociceptin Derivatives Are Potent Agonists
and Antagonists of ERK Phosphorylation
and Thermal Analgesia in Mice. Journal of
Medicinal Chemistry 53: 8400-8408.
Harrison, R.S., Shepherd, N.E., Hoang,
H.N., Ruiz-Gomez, G., Hill, T.A., Driver,
R.W., Desai, V.S., Young, P.R., Abbenante,
G., and Fairlie, D.P. (2010). Downsizing
human, bacterial, and viral proteins to short
water-stable alpha helices that maintain
biological potency. Proceedings of the
National Academy of Sciences of the
United States of America 107: 11686-
11691.
Henriques, S.T., and Castanho, M.A.R.B.
(2010). Is PrP(106-126) Fragment Involved
in the Membrane Activity of the Prion
Protein Current Protein and Peptide
Science 5: 326-333.
Henriques, S.T., Tan, C.C., Craik, D.J.,
and Clark, R.J. (2010). Structural and
Functional Analysis of Human Liver-
Expressed Antimicrobial Peptide 2.
Chembiochem 11: 2148-2157.
Heras, B., Totsika, M., Jarrott, R.,
Shouldice, S.R., Guncar, G., Achard,
M.E.S., Wells, T.J., Argente, M.P.,
McEwan, A.G., and Schembri, M.A. (2010).
Structural and Functional Characterization
of Three DsbA Paralogues from Salmonella
enterica Serovar Typhimurium. Journal of
Biological Chemistry 285: 18423-18432.
Huang, Y.-H., Colgrave, M.L., Clark,
R.J., Kotze, A.C., and Craik, D.J. (2010).
Lysine-scanning mutagenesis reveals an
amendable face of the cyclotide kalata B1
for the optimization of nematocidal activity.
Journal of Biological Chemistry 285:
10797-10805.
Ireland, D.C., Clark, R.J., Daly, N.L., and
Craik, D.J. (2010). Isolation, sequencing,
and structure - Activity relationships of
cyclotides. Journal of Natural Products 73:
1610-1622.
Iyer, A., Fairlie, D.P., Prins, J.B., Hammock,
B.D., and Brown, L. (2010). Inflammatory
lipid mediators in adipocyte function and
obesity. Nature Reviews Endocrinology 6:
71-82.
Iyer, A., Fenning, A., Lim, J., Le, G.T.,
Reid, R.C., Halili, M.A., Fairlie, D.P., and
Brown, L. (2010). Antifibrotic activity of an
inhibitor of histone deacetylases in DOCAsalt
hypertensive rats. British Journal of
Pharmacology 159: 1408-1417.
Jarrott, R., Shouldice, S.R., Guncar, G.,
Totsika, M., Schembri, M.A., and Heras,
B. (2010). Expression and crystallization
of SeDsbA, SeDsbL and SeSrgA from
Salmonella enterica serovar Typhimurium.
Acta Crystallographica Section F:
Structural Biology and Crystallization
Communications 66: 601-604.
Johnstone, K.D., Karoli, T., Liu, L., Dredge,
K., Copeman, E., Li, C.P., Davis, K.,
Hammond, E., Bytheway, I., Kostewicz, E.,
Chiu, F.C.K., Shackleford, D.M., Charman,
S.A., Charman, W.N., Harenberg, J.,
Gonda, T.J., and Ferro, V. (2010). Synthesis
and Biological Evaluation of Polysulfated
Oligosaccharide Glycosides as Inhibitors of
Angiogenesis and Tumor Growth. Journal
of Medicinal Chemistry 53: 1686-1699.
Kaas, Q., and Craik, D.J. (2010). Analysis
and classification of circular proteins in
CyBase. In: , Biopolymers Peptide Science.
Ist International Conference on Circular
Proteins, Heron Island, Qld, Australia, (584-
591). 18-21 October, 2009
Kaas, Q., Westermann, J.-C., and Craik,
D.J. (2010). Conopeptide characterization
and classifications: An analysis using
ConoServer. Toxicon 55: 1491-1509.
Khambati, H.K., Moraes, T.F., Singh, J.,
Shouldice, S.R., Yu, R.H., and Schryvers,
A.B. (2010). The role of vicinal tyrosine
residues in the function of Haemophilus
influenzae ferric-binding protein A.
Biochemical Journal 432: 57-64.
Kirkby, B., Roman, N., Kobe, B., Kellie,
S., and Forwood, J.K. (2010). Functional
and structural properties of mammalian
acyl-coenzyme A thioesterases. Progress
in Lipid Research 49: 366-377.
Kruse, O., and Hankamer, B. (2010).
Microalgal hydrogen production. Current
Opinion In Biotechnology 21: 238-243.
Landsberg, M.J., Ruggles, J.L., Hussein,
W.M., McGeary, R.P., Gentle, I.R., and
Hankamer, B. (2010). Molecular Packing
of Functionalized Fluorinated Lipids in
Langmuir Mono layers. Langmuir 26:
18868-18873.
Lewis, R.J., and Poli, M. (2010). Toxins in
Seafood. Toxicon 56: 107.
Liebscher, S., Stoermer, M.J., Watterson,
D., Chappell, K.J., Webb, R.I., Khromykh,
A.A., Fairlie, D.P., and Young, P.R. (2010).
Sneaking up on West Nile Virus NS2B/
NS3 protease subcellular activity utilising
dye-quenched substrates. In: Plusstrand
2010: The Ninth International Symposium
on Positive-Strand RNA Viruses, Atlanta,
GA, U.S.A.,17-21 May 2010
Loo, D., Jones, A., and Hill, M.M. (2010).
Lectin magnetic bead array for biomarker
discovery. Journal of Proteome Research
9: 5496-5500.
Loser, R., Abbenante, G., Madala, P.K.,
Halili, M., Le, G.T., and Fairlie, D.P. (2010).
Noncovalent tripeptidyl benzyl- And
cyclohexyl-amine inhibitors of the cysteine
protease caspase-1. Journal of Medicinal
Chemistry 53: 2651-2655.
Loser, R., Gut, J., Rosenthal, P.J., Frizler,
M., Gutschow, M., and Andrews, K.T.
(2010). Antimalarial activity of azadipeptide
nitriles. Bioorganic and Medicinal
Chemistry Letters 20: 252-255.
Loughlin, W.A., Tyndall, J.D.A., Glenn, M.P.,
Hill, T.A., and Fairlie, D.P. (2010). Update
1 of: Beta-strand mimetics. Chemical
Reviews 110: 1-38.
Luo, S., Akondi, K.B., Zhangsun, D., Wu,
Y., Zhu, X., Hu, Y., Christensen, S., Dowell,
C., Daly, N.L., Craik, D.J., Wang, C.-I.A.,
Lewis, R.J., Alewood, P.F., and McIntosh,
J. M. (2010). Atypical alpha-conotoxin
LtIA from Conus litteratus targets a novel
microsite of the alpha 3 beta 2 nicotinic
receptor. Journal of Biological Chemistry
285: 12355-12366.
Madala, P., Tyndall, J., David, A., Nall,
T., and Fairlie, D. (2010). Update 1 of:
Proteases universally recognize Beta
Strands in their active sites. Chemical
Reviews 110: 1-33.
Marles-Wright, J., and Lewis, R.J. (2010).
The stressosome: molecular architecture
of a signalling hub. Biochemical Society
Transactions 38: 928-933.