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2010 Annual Report - Institute for Molecular Bioscience - University ...

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5 executive reports<br />

DEPUTY DIRECTORS’ REPORT<br />

RESEARCH<br />

The end of 2009 marked the close of<br />

IMB’s first decade of existence and<br />

meant it was time <strong>for</strong> our second<br />

quinquennial review. This document<br />

contained some very pleasing statistics<br />

that demonstrated how we have grown<br />

and strengthened as an organisation.<br />

For example, in the five years from 2005<br />

to 2009, our competitive grant income<br />

from national and international sources<br />

grew to over $160m, which represented<br />

an increase of 87 percent from the<br />

first five years. Two thirds of our group<br />

leaders now support their own salaries<br />

with senior research fellowships, an<br />

increase of 50 percent in the number<br />

of fellowships since 2005. We have<br />

published over 1050 papers in the<br />

last five years, a 60 percent increase<br />

in output. Many of these papers were<br />

accepted in top-rank international<br />

journals such as Science, Nature and<br />

Cell, and in leading disciplinary journals.<br />

These publications were cited, on<br />

average, more than 3000 times per year,<br />

an increase of 74 percent from 2000-<br />

2004. Our success rates in NHMRC and<br />

ARC funding schemes are consistently<br />

higher than national and Queensland<br />

averages; particularly notable is our 90<br />

percent success rate <strong>for</strong> ARC Linkage<br />

grants.<br />

We aim to continue improving in the<br />

future. Our achievements from the first<br />

year of our second decade, outlined<br />

below, show that we are on track to<br />

achieve this aim.<br />

Professor Sean Grimmond was part of a<br />

worldwide collaboration that published a<br />

paper in Nature in April. The International<br />

Cancer Genome Consortium is working<br />

to map the genomes of 50 different<br />

types and subtypes of cancer. Professor<br />

Grimmond leads Australia’s research<br />

ef<strong>for</strong>t, which involves sequencing 500<br />

pancreatic and ovarian tumours in<br />

collaboration with Professor Andrew<br />

Biankin from the Garvan <strong>Institute</strong> and<br />

Professor David Bowtell from the Peter<br />

MacCallum Cancer Centre.<br />

As Professor Wainwright noted in his<br />

report, our grant results <strong>for</strong> <strong>2010</strong> were<br />

not as spectacular as 2009 but we still<br />

per<strong>for</strong>med well. The IMB received nearly<br />

$10 million <strong>for</strong> projects and equipment<br />

from the NHMRC and the ARC, and<br />

six IMB researchers were offered a<br />

total of seven fellowships from the two<br />

funding bodies. More details of these<br />

grants and fellowships can be found<br />

in the Highlights section beginning on<br />

page 10, however I would like to make<br />

particular mention of Dr Matt Sweet,<br />

who had the opportunity to take up<br />

both an ARC Future Fellowship and an<br />

NHMRC Research Fellowship. Dr Sweet<br />

was appointed as a group leader at<br />

IMB in 2007, and his excellent results in<br />

these fellowship rounds are a testament<br />

to his leadership and the quality of his<br />

research.<br />

Professor John Mattick’s Australia<br />

Fellowship (see Professor Wainwright’s<br />

report, preceding page, or Highlights<br />

section on page 10, <strong>for</strong> more details)<br />

means the IMB is now home to four<br />

recipients of this highly regarded award<br />

<strong>for</strong> medical research, and we are the<br />

only research institute in Australia to<br />

have received an Australia Fellowship<br />

every year since the program’s inception.<br />

While we rightly recognise our winners<br />

of national fellowships, the IMB is also<br />

committed to providing opportunities<br />

to support the work of outstanding<br />

early-career researchers to facilitate their<br />

move towards independent researcher<br />

status. With this in mind, the institute’s<br />

executive committee decided in <strong>2010</strong><br />

to create the IMB Fellowship scheme.<br />

Exceptional researchers from among<br />

our postdoctoral scientists would be<br />

selected to receive financial support<br />

<strong>for</strong> their projects, with up to four ‘IMB<br />

Fellows’ resident at the <strong>Institute</strong> at any<br />

one time.<br />

Dr Joshua Mylne from the Craik group<br />

was chosen as the inaugural IMB Fellow.<br />

Dr Mylne was originally a botanist who<br />

studied vernalisation – the process<br />

by which plants sense cold and alter<br />

their flowering time. Within the Craik<br />

group, which has a strong focus on<br />

developing improved protein frameworks<br />

<strong>for</strong> drugs, Dr Mylne has been examining<br />

the potential of a mechanism within<br />

sunflower seeds to manufacture peptide<br />

drugs cheaply and quickly. This project<br />

would allow the efficient production<br />

of drugs, particularly in third-world<br />

We aim to continue improving in<br />

the future. Our achievements from the<br />

first year of our second decade,<br />

outlined here, show that we are on<br />

track to achieve this aim<br />

’’<br />

– Professor Jenny Stow<br />

Deputy Director (Research)

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