DC beads loaded with Irinotecan : precilinical and early clinical ...
DC beads loaded with Irinotecan : precilinical and early clinical ...
DC beads loaded with Irinotecan : precilinical and early clinical ...
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Tumor necrosis<br />
110%<br />
Tumor necrosis<br />
100<br />
90%<br />
70%<br />
50%<br />
30%<br />
IV IA TACE<br />
Necrosis (%)<br />
80<br />
60<br />
40<br />
20<br />
Damaged<br />
Necrosis<br />
10%<br />
-10%<br />
1H 6H 24H<br />
0<br />
DEB1h DEB12h DEB24h DEB3d DEB7d DEB14d<br />
(Hong K, et al. Clin Cancer Res 2006;12:2563–7)<br />
• Baseline necrosis of 30%, usual in VX2 tumor<br />
• Equivalent percent of onecrosis for IA & TACE @ 6 h<br />
• Significantly higher necrosis for TACE @ 24 h
![Drug-Eluting Bead TACE with DC Bead® [DEBDOXâ¢] in the ...](https://img.yumpu.com/50840371/1/184x260/drug-eluting-bead-tace-with-dc-beadar-debdoxa-in-the-.jpg?quality=85)
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