The Use of NT-proBNP and BNP as Biomarkers of Acute Heart Failure
The Use of NT-proBNP and BNP as Biomarkers of Acute Heart Failure
The Use of NT-proBNP and BNP as Biomarkers of Acute Heart Failure
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Age-independent Rule-out Cut-point<br />
• International Collaborative <strong>of</strong> <strong>NT</strong>-<strong>pro<strong>BNP</strong></strong> (ICON) Study data (acute setting):<br />
• 300 pg/ml, age independent<br />
• 99% sensitive<br />
• 60% specific<br />
• 98% NPV<br />
Source: Januzzi et al, Eur <strong>Heart</strong> J (2006) 27: 839-845.<br />
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