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The Use of NT-proBNP and BNP as Biomarkers of Acute Heart Failure

The Use of NT-proBNP and BNP as Biomarkers of Acute Heart Failure

The Use of NT-proBNP and BNP as Biomarkers of Acute Heart Failure

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<strong>NT</strong>-<strong>pro<strong>BNP</strong></strong> Concentrations<br />

B<strong>as</strong>eline Follow-up P<br />

Overall 2118 1321 .02<br />

By treatment allocation<br />

Treatment B<strong>as</strong>eline Follow-up P<br />

SOC 1946 1844 .61<br />

<strong>NT</strong>-<strong>pro<strong>BNP</strong></strong> 2344 1125 .01<br />

P = .03 for SOC follow-up versus <strong>NT</strong>-<strong>pro<strong>BNP</strong></strong> follow-up<br />

44.3% <strong>of</strong> <strong>NT</strong>-<strong>pro<strong>BNP</strong></strong> subjects 1000 pg/mL<br />

Source: Januzzi et al. clinicaltrialresults.org/Slides/PROTECT%20Presentation%20FINAL.ppt, accessed March 27, 2012<br />

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