The Use of NT-proBNP and BNP as Biomarkers of Acute Heart Failure
The Use of NT-proBNP and BNP as Biomarkers of Acute Heart Failure
The Use of NT-proBNP and BNP as Biomarkers of Acute Heart Failure
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B-type Natriuretic Peptides<br />
Pre-Pro-<strong>BNP</strong> 1-134<br />
26-aa signal<br />
sequence<br />
Pro-<strong>BNP</strong> 1-108<br />
WALL<br />
STRESS<br />
N-terminal<br />
Pro-<strong>BNP</strong> 1-76<br />
t 1/2 = 60-120 min<br />
<strong>BNP</strong> 77-108<br />
t 1/2 = 18 min<br />
Source: Medscape.com (10/12/2009)<br />
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