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ERF: 3,000 subjects in 20,000 pedigree QTL/MAS Workshop, May 2010, Poznan Yurii Aulchenko
Analysis of large complex pedigrees • ML/REML not feasible: take years for a single GWA scan to be analysed • What are the options – Genomic control (general technique to account for populational confounding) – Approximations to ML: FASTA, GRAMMAS, … new staff QTL/MAS Workshop, May 2010, Poznan Yurii Aulchenko
Page 1 and 2: Methods for GWA analysis in samples
Page 3 and 4: Reasons for genetic association Wha
Page 5 and 6: Genetic origin is a major confounde
Page 7 and 8: Skin color scan GWAS of skin color
Page 9 and 10: Genome-Wide Association analysis
Page 11: Nuclear pedigree QTL/MAS Workshop,
Page 15 and 16: Idea of the genomic control • Mod
Page 17 and 18: Few notes on GC When stratification
Page 19 and 20: GRAMMAS-GC GW Rapid Association usi
Page 21 and 22: Relationship between genomes The es
Page 23 and 24: Genomic Φ is better than pedigree
Page 25 and 26: Recent developments: even better GR
Page 27 and 28: Recent developments: binary traits

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