Correlation

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Outline • Samples congaing relatives: – Human genetically isolated populations – Any (sub-)total ascertainment (>10% population) – Animal data • Reasons for genetic association • (Genome-Wide) Association analysis in pedigrees • Recent developments QTL/MAS Workshop, May 2010, Poznan Yurii Aulchenko
Reasons for genetic association What we see Phenotype Correlation Genotype Phenotype Causation Genotype True model Correlation Confounder Correlation Phenotype Genotype QTL/MAS Workshop, May 2010, Poznan Secondary correlation Yurii Aulchenko
Page 1: Methods for GWA analysis in samples
Page 5 and 6: Genetic origin is a major confounde
Page 7 and 8: Skin color scan GWAS of skin color
Page 9 and 10: Genome-Wide Association analysis
Page 11 and 12: Nuclear pedigree QTL/MAS Workshop,
Page 13 and 14: Analysis of large complex pedigrees
Page 15 and 16: Idea of the genomic control • Mod
Page 17 and 18: Few notes on GC When stratification
Page 19 and 20: GRAMMAS-GC GW Rapid Association usi
Page 21 and 22: Relationship between genomes The es
Page 23 and 24: Genomic Φ is better than pedigree
Page 25 and 26: Recent developments: even better GR
Page 27 and 28: Recent developments: binary traits

Correlation

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