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SPRING - UCSC Extension Silicon Valley

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Bioinformatics Biosciences<br />

16-unit minimum<br />

Required Courses<br />

Bioinformatics Tools,<br />

Databases and Methods<br />

CMPS.X446.4 (3.0 quarter units)<br />

This course provides a practical introduction to the<br />

main public domain tools, databases and methods used<br />

in bioinformatics, including DNA and protein databases<br />

such as Genbank and PBD, software tools such as BLAST,<br />

and methods including those for aligning sequences. It<br />

emphasizes the needs of the user of bioinformatics tools<br />

and databases, rather than complex algorithm development<br />

and advanced computational methods. Computer<br />

lab exercises and online demonstrations of the various<br />

databases and tools on the Internet are included.<br />

This course is intended both for life scientists and<br />

computer engineers. After the prerequisite, this is the<br />

recommended first course for those wanting to gain<br />

skills in bioinformatics.<br />

Prerequisite(s): “Molecular Biology, Introduction.”<br />

LELAND KOZAR, M.B.A., M.A., M.S.<br />

SANTA CLARA LAB WITH ONLINE MATERIALS<br />

10 meetings: Mondays, 6–9 pm, April 23–May 21;<br />

Saturdays, 9 am–12 pm, April 21–May 19.<br />

Fee: $765 ($76.50 discount for early enrollment).<br />

To enroll, use Section Number 2447.(043)<br />

BIOINFORMATICS CERTIFICATE<br />

Prerequisite Courses units Course F W Sp Su<br />

Molecular Biology, Introduction.............................................3.0...........4213 n n n<br />

AND<br />

Statistics OR.........................................................................5.0.........23588 m m m<br />

Statistical Design of Experiments: A Practical Approach......2.0.........23096<br />

Required Courses units Course F W Sp Su<br />

Bioinformatics Tools, Databases and Methods.......................3.0...........2447 n n m<br />

Experimental Methods in Molecular Biology.........................3.0...........1912<br />

n<br />

Statistical Analysis and Modeling for Bioinformatics<br />

and Biomedical Applications ............................................3.0...........1032 n n<br />

Elective Courses (7 units required) Units Course F W Sp Su<br />

Take required courses before electives.<br />

Cellular Biology .....................................................................3.0...........3383 n<br />

Computational Biology with Java .........................................3.0...........0266 n<br />

* Computational Intelligence....................................................1.5.........19951 n n<br />

DNA Microarrays: Principles, Applications and Data Analysis.. 3.0...........2183<br />

n<br />

Drug Discovery, Introduction .................................................3.0...........4853 n n<br />

Gene Expression and Pathways.............................................2.0...........6020<br />

n<br />

Molecular Diagnostics............................................................1.5.........21972 n n<br />

Perl for Bioinformatics............................................................2.0.........19971<br />

* Sequence Analysis in Bioinformatics, Advanced ....................2.0...........0036<br />

Structure Analysis of Biological Molecules.............................2.0...........5925 n<br />

* Suggested electives for computer scientists and IT professionals<br />

n held in classroom m offered online p both classroom and online sessions are available<br />

Visit ucsc-extension.edu for the most current program schedule.<br />

Experimental Methods<br />

in Molecular Biology<br />

NATSC.X446.5 (3.0 quarter units)<br />

This lecture-based course provides a theoretical overview<br />

of the key molecular biology techniques used in basic<br />

life science research and by the biotechnology and<br />

biopharmaceutical industry for the discovery of novel<br />

therapeutics. Topics include gene cloning, manipulation<br />

and sequencing; PCR; RNA interference; gene expression<br />

analysis; protein expression, engineering, and structure<br />

determination; and the fundamentals of experimental<br />

design. Also addressed are high-throughput sequencing<br />

and microarray expression analysis and the types of data<br />

these techniques generate.<br />

Prerequisite(s): “Molecular Biology, Introduction.”<br />

RAXIT JARIWALLA, Ph.D.<br />

SANTA CLARA CLASSROOM<br />

10 meetings: Mondays, 6–9 pm, June 18–August 6;<br />

Saturdays, 1–4 pm, June 23–August 4<br />

(5 no meetings TBA).<br />

Fee: $765 ($76.50 discount for early enrollment).<br />

To enroll, use Section Number 1912.(039)<br />

Statistical Analysis and<br />

Modeling for Bioinformatics<br />

and Biomedical Applications<br />

CMPS.X445.1 (3.0 quarter units)<br />

This course presents the statistical methods most frequently<br />

used in bioinformatics and biomedical research.<br />

Topics include probability, hypothesis testing, confidence<br />

intervals, t-tests, analysis of variance, regression analysis,<br />

power and sample size, and simulations. Students perform<br />

statistical analyses using the R programming language.<br />

Examples are drawn from biomedical applications, such<br />

as gene expression analysis, molecular diagnostics, and<br />

evaluation of new drugs and medical devices.<br />

Prerequisite(s): “Statistics.”<br />

MICHAEL ELASHOFF, Ph.D.<br />

SANTA CLARA LAB WITH ONLINE MATERIALS<br />

10 meetings: Thursdays, 6–9 pm, April 12–June 28<br />

(2 no meetings TBA).<br />

Fee: $765 ($76.50 discount for early enrollment).<br />

To enroll, use Section Number 1032.(039)<br />

Elective Courses<br />

DNA Microarrays: Principles,<br />

Applications and Data Analysis<br />

For course description, see page 10.<br />

Drug Discovery, Introduction<br />

For course description, see page 9.<br />

Gene Expression and Pathways<br />

NATSC.X426.2 (2.0 quarter units)<br />

This course provides a solid foundation in the molecular<br />

concepts and cutting-edge technologies that are central<br />

to the understanding of gene expression pathways<br />

in simple cells and complex multicellular organisms.<br />

Topics include gene structure; regulatory proteins and<br />

transcriptional control; inheritance of states of gene<br />

expression; and posttranscriptional control of gene<br />

activity. Abnormalities in gene expression are discussed<br />

in relation to human disease states as well as drug<br />

discovery and diagnostic medicine.<br />

Prerequisite(s): “Molecular Biology, Introduction” or<br />

equivalent or basic knowledge of foundation concepts<br />

in molecular biology.<br />

RAXIT JARIWALLA, Ph.D.<br />

SANTA CLARA CLASSROOM<br />

10 meetings: Mondays, 6–9 pm, April 4–May 2;<br />

Saturdays, 1–4 pm, April 9–May 7 (2 no meetings TBA).<br />

Fee: $715 ($71.50 discount for early enrollment).<br />

To enroll, use Section Number 6020.(023)<br />

Molecular Diagnostics<br />

For course description, see page 11.<br />

To pursue two bioscience-related<br />

certificates in parallel or in sequence,<br />

see page 7.<br />

8<br />

Enroll on our Web site with a credit card. It’s the fastest, easiest way to get started. Visit ucsc-extension.edu.

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