Current issues in Hereditary Angioedema (HAE) - Ipopi

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Prevention vs treatment Prevention (prophylaxis) Treatment •C1 inhibitor (‘Berinert’, ‘Cetor/Cinryze’) •Icatibant (‘Firazyr’) •(Ecallantide/ ‘Kalbitor’) •(Recombinant C1 inhibitor ‘Ruconest’) – Danazol/stanozolol/ oxandrolone “attenuated androgens” – Tranexamic acid Tablets Injections
What have we learnt about the new • C1 inhibitor (Berinert) treatments We need to use a higher dose- 3 vials for an average sized person 25 kg 4 st 1 vial (500 units) 50kg 8 st 2 vials (1000 units) 75 Kg 12 st 3 vials (1500 units) 100 kg 16 stone 4 vials (2000 units)
Page 1 and 2: Current issues in Hereditary Angioe
Page 3 and 4: What is HAE (Hereditary • HAE 1 o
Page 5: C1 inhibitor controls inflammation
Page 9 and 10: • Berinert (C1 inhibitor) trials
Page 11 and 12: Treatment of C1 inhibitor deficienc
Page 13 and 14: Icatibant (Firazyr) • Recurrent a
Page 15 and 16: Living with hereditary angioedema:
Page 17 and 18: L’s story: 25 year old with HAE
Page 19 and 20: L’s story •15 th March 2010- 2
Page 21 and 22: Treatment of C1 inhibitor deficienc
Page 23 and 24: Self administration C1 ınhıbıtor
Page 25 and 26: C1 inhibitor controls local Healthy
Page 27: Rational use of steroids….
Page 30 and 31: Mr B 15 years • Unwilling to trai
Page 32 and 33: Mrs B 42 years • Danazol 100 mg a
Page 34 and 35: Need to control acute attacks
Page 36 and 37: What does everyone want • Patient
Page 38: Recent initiatives • World consen

Current issues in Hereditary Angioedema (HAE) - Ipopi

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