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Chronic Kidney Disease Pathway Document Description Presented ...

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Diabetes<br />

All people with diabetes should receive annual assessment of microalbumin and<br />

albumin/creatinine ratio.<br />

If raised ACR :<br />

• ACR >2.5mg/mmol (male)<br />

• ACR >3.5mg/mmol (female)<br />

or<br />

• Microalbumin level > 30 mg/day<br />

Repeat test at next two clinic visits over 3–4 months<br />

Microalbuminuria is confirmed if at least one out of two or more results is also<br />

raised. http://www.nice.org.uk/nicemedia/pdf/CG66T2DQRG.pdf<br />

Microalbuminuria with eGFR >60ml/min/1.73m 2 is stage 1 / 2 CKD.<br />

In patients with diabetes (type 1 or type 2), microalbuminuria/proteinuria is an<br />

indication for:<br />

• Treatment with ACE inhibitors (or Angiotensin receptor blockers if those<br />

are not tolerated), with titration up to maximum dose or maximum<br />

tolerated dose irrespective of initial blood pressure<br />

• Control of hypertension to target<br />

• Tight glycaemic control<br />

• Monitoring of ACR, serum creatinine and eGFR.<br />

• Consider referral to / discussion with the diabetic team or joint<br />

diabetic/nephrology clinic for review<br />

• Consider referral to Nephrologist. See referral criteria<br />

Blood<br />

Microscopic haematuria without proteinuria, eGFR >60ml/min<br />

• Age >50, refer to Urology<br />

• Age 50 with negative urological investigations, treat as CKD<br />

stage<br />

Microscopic haematuria with proteinuria eGFR >60ml/min<br />

• Refer nephrology<br />

42

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