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Training Manual for Preventive Malaria - Ministry of Health

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cells. About 1 to 2 weeks later, the parasites are released into the blood, at which time the<br />

person starts showing symptoms <strong>of</strong> malaria.<br />

The parasites then attack red blood cells leading to breakdown <strong>of</strong> the cells, which then may<br />

lead to anaemia.<br />

LIFE CYCLE OF MALARIA PARASITE<br />

MOSQUITO VECTOR<br />

Sporozoites in salivary<br />

gland<br />

sporozoites<br />

MAN<br />

Liver schizogony<br />

Liver Hypnozoites<br />

(po, pv<br />

oocyst<br />

merozoites<br />

PRBCs<br />

Figure 1:<br />

ookinite<br />

zygote<br />

Gametes (? ? )<br />

Gametocytes (? ?)<br />

trophozoite<br />

schizonts<br />

Rupt. RBCs<br />

Sequestration (pf)<br />

1.2: POPULATIONS MOST AFFECTED BY MALARIA<br />

<strong>Malaria</strong> is a public health problem throughout the world. Of the estimated 300 million cases<br />

each year worldwide, more than 90% occur in Sub-Saharan Africa. Young children and<br />

pregnant women are two groups <strong>of</strong> people most at risk <strong>of</strong> infection. Other people who are also<br />

at a greater risk <strong>of</strong> being infected with the malarial parasite include immigrants, refugees,<br />

people with sickle cell anaemia or HIV/AIDS and visitors from areas with little or no malaria<br />

(low malaria transmission areas) who come to visit or live in high malaria transmission areas.<br />

Every hour 4 persons in Ghana die from malaria <strong>of</strong> which two are children under five<br />

(2002)<br />

Among pregnant women, malaria accounts <strong>for</strong> 13.8% <strong>of</strong> OPD attendance and 10.6% <strong>of</strong><br />

admissions<br />

Women in their first or second pregnancies are more at risk<br />

<br />

Pregnant women are twice more likely to become infected than non-pregnant women<br />

<strong>Malaria</strong> contributes 9.4% <strong>of</strong> maternal deaths<br />

11

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