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Comparative Genomics-Basic and Applied Research.pdf

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28 <strong>Comparative</strong> <strong>Genomics</strong><br />

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of linker length <strong>and</strong> rigidity. Nucleic Acids Res. 29, 1565–1573 (2001).<br />

66. Roychowdhury, A., Illangkoon, H., Hendrickson, C. L. & Benner, S. A. 2-Deoxycytidines<br />

carrying amino <strong>and</strong> thiol functionality: synthesis <strong>and</strong> incorporation by Vent<br />

(exo-) polymerase. Org. Lett. 6, 489–492 (2004).<br />

67. Gourlain, T. et al. Enhancing the catalytic repertoire of nucleic acids. II. Simultaneous<br />

incorporation of amino <strong>and</strong> imidazolyl functionalities by two modified triphosphates<br />

during PCR. Nucleic Acids Res. 29, 1898–1905 (2001).<br />

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of thermostable DNA polymerases from hyperthermophilic marine Archaea with<br />

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RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase<br />

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Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides.<br />

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71. Fa, M., Radeghieri, A., Henry, A. A. & Romesberg, F. E. Exp<strong>and</strong>ing the substrate<br />

repertoire of a DNA polymerase by directed evolution. J. Am. Chem. Soc. 126, 1748–<br />

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73. Lewis, E. K. et al. Color-blind fluorescence detection for four-color DNA sequencing.<br />

Proc. Natl. Acad. Sci. U. S. A. 102, 5346–5351 (2005).

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