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Health Bulletin 2009

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GLP (Good Laboratory Practice) 10 ‐ 4 110 100 ‐ 50 140 ‐<br />

GLP (Good Laboratory Practice) 25 ‐ ‐ ‐ ‐ ‐ ‐ ‐ ‐<br />

GLP (Good Laboratory Practice) 20 ‐ ‐ ‐ ‐ ‐ ‐ ‐ ‐<br />

GLP (Good Laboratory Practice) 14 ‐ ‐ ‐ ‐ ‐ ‐ ‐ ‐<br />

GLP (Good Laboratory Practice) 5 ‐ 20 60 40 ‐ ‐ ‐ 240<br />

Computer Training (Refresher) 14 6 2 13 ‐ ‐ 25 50 ‐<br />

Security Management Training 5 ‐ ‐ ‐ ‐ ‐ ‐ ‐ 30<br />

English Language Training 28 ‐ ‐ ‐ ‐ 40 51 ‐ ‐<br />

Source: IPH, Mohakhali, Dhaka<br />

Diagnosis of bronchiolitis may be masked under cover of pneumonia leading to improper<br />

management: findings of ICMH study<br />

Bronchiolitis remains a major public health problem throughout the world exerting significant morbidity<br />

and mortality. Bronchiolitis due to Respiratory syncytial virus (RSV) remains a significant cause of<br />

respiratory disease all over the world including South-East Asian countries like India and Pakistan. It<br />

is estimated that proportional morbidity among the infants of Bangladesh due to respiratory diseases<br />

is 45%. In 2001-2002, epidemic of bronchiolitis was first reported in the country and high rate of this<br />

disease continued to prevail over the next five years. A recent study by Kabir, et al of Institute of Child<br />

and Mother <strong>Health</strong> shows 21% prevalence of bronchiolitis among the u-5 children who attended<br />

different<br />

hospitals. It is found that nearly 95% of bronchiolitis cases are of viral origin, RSV being the<br />

commonest. The diagnosis of bronchiolitis is most often made on clinical grounds and the criteria may<br />

vary. Very simply, the first attack of wheezing in a previously healthy child of less than two years of<br />

age or for a diverse criteria with coryzal symptoms followed by rapid onset of wheeze, fever,<br />

tachypnea, chest retractions, crepitation, ronchi with radiographic evidence of chesthyperinflation. The<br />

study undertook middle line as the diagnostic criteria for<br />

bronchiolitis (runny nose followed by breathing difficulty, chest indrawing and rhonchi (on auscultation)<br />

in children aged less than 2 years. Misdiagnosis of bronchiolitis as pneumonia has been observed,<br />

where antibiotics, have been used indiscriminately in 99% cases. Proportion of costly antibiotics, such<br />

as, ceftriaxone, a third generation cephalosporine, was in high proportion. Treatment for bronchiolitis<br />

require home management (in milder cases) and oxygen therapy or in severe cases measures such<br />

as nebulized salbutamol, adrenaline, corticosteroids, aerosolized ribavirin, hypertonic saline and in<br />

some cases critical management in pediatric intensive care unit (PICU). However, antibiotics remain a<br />

common practice in treating bronchiolitis despite the rare likelihood of bacterial infection. Use of<br />

antibiotics increases treatment cost and facilitates bacterial resistance. A recent multi-centre<br />

randomized control trial conducted by Kabir, et al have shown that managing acute bronchiolitis<br />

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