Protein-Protein Interactions, Networks and Pathways - Chagall
Protein-Protein Interactions, Networks and Pathways - Chagall
Protein-Protein Interactions, Networks and Pathways - Chagall
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Computational ChallengesI:Data description• The identity of the interacting proteins is notalways clear. Gene names, differentIdentifiers, alternative splicing, experimentalconstructs - a major resource expend.• Post translational modification. Not easy todescribe <strong>and</strong> can be very complex (e.g.glycosylation).• Conditions <strong>and</strong> context are often missing. Invitro experiments may lack the time/spatialcomponents of interactions.
Change language