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Protein-Protein Interactions, Networks and Pathways - Chagall

Protein-Protein Interactions, Networks and Pathways - Chagall

Protein-Protein Interactions, Networks and Pathways - Chagall

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Mapping PPI to a Graph• A simple mapping– compound=node, interaction=edge• A more realistic mapping– Cell localization, cell cycle, cell type, taxonomy– Only represent physiologically relevantinteraction networks• Visualizing large datasets– Collapsing redundancies to a single node– Hierarchical organization (pathways,complexes).

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