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Protein-Protein Interactions, Networks and Pathways - Chagall

Protein-Protein Interactions, Networks and Pathways - Chagall

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Gibbs Sampling• Gibbs sampling is a Markov Chain MonteCarlo (MCMC) algorithm that samples froman unknown joint distribution using the knownconditional probabilities.• Commonly used (in bioinformatics) for motifdiscoverysuch as, transcription factorsbinding sites.• Provides a mechanism for incorporating priorknowledge about the length <strong>and</strong> compositionof the motif.

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